Immobilized Anti-GUCY2C Antibody, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human with the EC50 of 30.6 ng/ml determined by ELISA.

The purity of GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Biotinylated GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human

Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.

产品编号	Z03913
规格	100 μg 500 μg 大单询价
数量
价格	￥5700


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产品简介

Species

Human

Protein Construction

GUCY2C/Guanylyl cyclase C (Ser24-Gln430) Accession # P25092-1	His	Avi
N-term		C-term

Conjugate

Biotin

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Anti-GUCY2C Antibody at 1 μg/ml (100μl/Well) on the plate can bind GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human (Cat.No.: Z03913)

Expression System

HEK293

Theoretical Molecular Weight

48.8 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

The purity of GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Biotinylated GUCY2C/Guanylyl cyclase C[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

技术背景

Target Background	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Synonyms	Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.