EGFR/HER1, His, Mouse captured on CM5 Chip via anti-his antibody can bind Mouse EGF, hFc Tag with an affinity constant of 3.98 nM as determined in SPR assay (Biacore T200).

The purity of EGFR/HER1, His, Mouse is greater than 95% as determined by SEC-HPLC.

EGFR/HER1, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

EGFR/HER1, His, Mouse

The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

产品编号	Z03922
规格	100 μg 500 μg 大单询价
数量
价格	￥2950


联系我们

产品简介

Species

Mouse

Protein Construction

EGFR/HER1 (Leu25-Ser647) Accession # Q01279	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

EGFR/HER1, His, Mouse (Cat.No.: Z03922) captured on CM5 Chip via anti-his antibody can bind Mouse EGF, hFc Tag in SPR assay (Biacore T200).

Expression System

HEK293

Theoretical Molecular Weight

70.40 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4 .

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

EGFR/HER1, His, Mouse captured on CM5 Chip via anti-his antibody can bind Mouse EGF, hFc Tag with an affinity constant of 3.98 nM as determined in SPR assay (Biacore T200).

The purity of EGFR/HER1, His, Mouse is greater than 95% as determined by SEC-HPLC.

EGFR/HER1, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

技术背景

Target Background

Synonyms

ErbB; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.