目录产品 » FOLR1, His, Mouse
FOLR1, His, Mouse

FOLR1, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

FOLR1, His, Mouse

The purity of FOLR1, His, Mouse is greater than 95% as determined by SEC-HPLC.

FOLR1, His, Mouse

Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.
Z03929
￥3200

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产品简介
Species Mouse
Protein Construction
FOLR1 (Thr25-Ser232)
Accession # P35846		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 25.36 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 33-43 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4 .
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例
  • FOLR1, His, Mouse
    • FOLR1, His, Mouse

    FOLR1, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • FOLR1, His, Mouse
    • FOLR1, His, Mouse

    The purity of FOLR1, His, Mouse is greater than 95% as determined by SEC-HPLC.


技术背景
Target Background Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.
Synonyms FR-alpha; FR alpha; FR α; FOLR; FOLR1; FBP; Folbp1; KB cells FBP; MOv18; Folate receptor 1; Fbp1; Folate receptor alpha;

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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