The purity of VEGF R2/KDR mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

VEGF R2/KDR mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human VEGF165,No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for VEGF R2/KDR mFc Chimera, Human with the EC50 of 42.7 ng/ml determined by ELISA.

VEGF R2/KDR mFc Chimera, Human

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.

产品编号	Z03966
规格	100 μg 500 μg 大单询价
数量
价格	￥2700


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产品简介

Species

Human

Protein Construction

VEGF R2/KDR (Ala20-Glu764) Accession # P35968-1	mFc (IgG1)
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Human VEGF165 at 1 μg/ml (100μl/well) on the plate can bind VEGF R2/KDR mFc Chimera, Human (Cat.No.: Z03966)

Expression System

HEK293

Theoretical Molecular Weight

110 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 150-200 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

The purity of VEGF R2/KDR mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

VEGF R2/KDR mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human VEGF165,No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for VEGF R2/KDR mFc Chimera, Human with the EC50 of 42.7 ng/ml determined by ELISA.

技术背景

Target Background	Vascular endothelial growth factor receptor 2 (VEGFR2) is one kind of tyrosine kinase receptors. VEGFR2 acts as a cell-surface receptor for VEGFA, VEGFB and PGF. It plays an important role in the development of embryonic vasculature, cell survival and cancer cell invasion. VEGFR2 is a key regulator of angiogenesis.
Synonyms	CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.