Species |
Cynomolgus |
Protein Construction |
His |
CD69/CLEC2C (Ser62-Lys199) Accession # XP_005570146.1 |
N-term |
C-term |
|
Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
16.91 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 23-28 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits. |
Synonyms |
CD69; CLEC2C; EA1; BL-AC/P26; AIM; BL-AC; P26; GP32; 28; MLR-3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.