CD19, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind CD19, His, Cynomolgus/Rhesus macaque with an affinity constant of 0.46 μM as determined in SPR assay (Biacore T200).

CD19, His, Cynomolgus/Rhesus macaque

CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.

产品编号	Z04141
规格	100 μg 500 μg 大单询价
数量
价格	￥3500


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产品简介

Species

Cynomolgus/Rhesus macaque

Protein Construction

CD19 (Gln21-Trp291) Accession # A0A2K5W8L9	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

AntiCD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind CD19, His, Cynomolgus/Rhesus macaque in SPR assay (Biacore T200). Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

30.96 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

CD19, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind CD19, His, Cynomolgus/Rhesus macaque with an affinity constant of 0.46 μM as determined in SPR assay (Biacore T200).

技术背景

Target Background

Synonyms

CD19; B4; CVID3; Leu-12; MGC12802

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.