| Species |
Human |
| Protein Construction |
| His |
CD72 (Arg117-Asp359)
Accession # P21854 |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
29.17 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 32-40 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
CD72 (originally Lyb-2), a 45 kDa type II transmembrane glycoprotein. CD72 belongs to the calcium-dependent C-type lectin superfamily and shares sequence homology with CD23 (the B-cell-specific low-affinity Fc receptor for IgE) and the asialoglycoprotein receptors. It is expressed as a disulfide-linked homodimer from the pro-B through the mature B-cell stage, but it is downregulated on terminally differentiated plasma cells. |
| Synonyms |
Lyb-2; Lyb2; CD72; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
