| Species |
Mouse |
| Protein Construction |
CD21 (Ile12-Trp963)
Accession # P19070 |
His |
| N-term |
C-term |
|
| Purity |
> 90% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
106.03 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 130-160 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. -80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
CD21, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
| Target Background |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes. |
| Synonyms |
EBV receptor; CD21; C3DR; CR2; C3DRSLEB9; CVID7; SLEB9 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
