| Species |
Mouse |
| Protein Construction |
CD39/ENTPD1 (Thr38-Ile478)
Accession # P55772 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Measured by its ability to hydrolyze the 5'phosphate groups from the substrate adenosine5'triphosphate (ATP). The specific activity is >18,000 pmol/min/µg. Test result meets the standard. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
50.72 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 68-78 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in 20mM Tris-HCl, 150mM NaCl (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues.CD39 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases . |
| Synonyms |
NTPDase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Entpd1; ADPase; ATPDase; NTPD1; NTPDase 1; NTPDase-1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
