Immobilized Human CD40, hFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for CD40 Ligand/TNFSF5 Trimer [Biotin], His & Flag, Human, His Tag with the EC50 of 47.6 ng/ml determined by ELISA.
The purity of CD40 Ligand/TNFSF5 Trimer [Biotin], His & Flag, Human is greater than 95% as determined by SEC-HPLC.
CD40 Ligand/TNFSF5 Trimer [Biotin], His & Flag, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD40 Ligand/TNFSF5 Trimer [Biotin], His & Flag, Human
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
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