| Species |
Human |
| Protein Construction |
KIR3DL3 (Glu26-Leu322)
Accession # Q8N743 |
His |
Avi |
| N-term |
|
C-term |
|
| Conjugate |
Biotin |
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Human B7H7, hFc Tag captured on CM5 Chip via Protein A can bind KIR3DL3[Biotin], His & Avi, Human in SPR assay (Biacore T200). Test result was comparable to standard batch. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
35.3 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl, 0.2M L-arginine (pH 8.2). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (PBMC) and decidual natural kill (NK) cells. |
| Synonyms |
CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
