Species |
Cynomolgus |
Protein Construction |
His |
ASGR1 (Gln62-Leu291) Accession # XP_005582755.1 |
N-term |
C-term |
|
Purity |
> 95% as determined by BisTris PAGE > 90% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
27.43 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS, 200mM Arginine (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
ASGR1 is a liver-specific surface marker that is exclusively expressed in liver and mediates internalization and lysosomal degradation of blood asialoglycoproteins. |
Synonyms |
ASGP-R 1; ASGPR 1; Hepatic lectin 1; HL-1; mHL-1; Asgr1; Asgr-1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.