Species |
Human |
Protein Construction |
EPHA2 (Ala24-Val537) Accession # P29317-1 |
His |
N-term |
C-term |
|
Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
57.56 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 58-65 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
Erythropoietin-producing hepatocellular receptor A2 (EphA2) receptor tyrosine kinase plays an important role in tissue organization and homeostasis in normal organs. EphA2 is overexpressed in a variety of types of solid tumours with oncogenic functions. |
Synonyms |
Ephrin type-A receptor 2; Epithelial cell kinase; ECK; MPK-5; MPK5; SEK-2; SEK2; Myk2; AW54528 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.