| Species |
Human |
| Protein Construction |
FOLR3 (Gln23-Ser245)
Accession # P41439-1 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
26.63 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 32-45 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
FOLR3 (Folate Receptor 3) is a member of the folate receptor family that plays a role in the transport of folic acid and its derivatives. It is a secretory protein that is not membrane-bound and is thought to enhance the bioavailability of folic acid, which in turn can reduce plasma homocysteine (Hcy) levels. Elevated Hcy levels are associated with an increased risk of various diseases, including neurodegenerative disorders and cardiovascular diseases. |
| Synonyms |
FR-gamma; Folate receptor 3; FR-G; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
