| Species |
Human |
| Protein Construction |
Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer [Phe23-Ser1122(ITGA10) acidic tail & Gln21-Asp728(ITGB1) basic tail]
Accession # O75578-1(ITGA10)&P05556-1(ITGB1) |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 0.1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
125.60 kDa (ITGA10) & 83.2 kDa (ITGB1) |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 130-160 kDa (ITGA10) and 110-120 kDa (ITGB1) based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts. |
| Synonyms |
Integrin alpha 10 beta 1; ITGA10&ITGB1; α10β1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
