Species |
Human |
Protein Construction |
MBL2/Mannan Binding Lectin (Glu21-Ile248)_x000D_ Accession # P11226 |
His |
N-term |
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
25.11 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
Mannan-binding lectin (MBL) is a vital element in the host innate immune system, which is primarily produced by the liver and secreted into the circulation.It is present in serum and may bind to a plethora of microbial pathogens and mediate opsonization of these by complement-dependent and/or independent mechanisms. |
Synonyms |
MBP-C; MBPC; MBL2; Mannan Binding Lectin; Collectin-1; MBP1; COLEC1; MBL;HSMBPC; MBL2D; MBPD |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.