| Species |
Human |
| Protein Construction |
PLXNA1 (Glu27-Pro1244)_x000D_
Accession # Q9UIW2 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
135 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 140-155 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and bind the class 3 semaphorins indirectly via Neuropilin-1 and -2. |
| Synonyms |
Plexin A1, Semaphorin receptor NOV, NOV, PLXN1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
