| Species |
Human |
| Protein Construction |
SFRP1/SARP2 (Ser32-Lys314)_x000D_
Accession # Q8N474 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
33.63 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 43-48 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to the loss of expression in various human cancers, which is mainly attributed by epigenetic inactivation via DNA methylation or transcriptional silencing by microRNAs. |
| Synonyms |
Secreted frizzled-related protein 1; FRP-1; FRP1; sFRP-1; Secreted apoptosis-related protein 2; SARP-2; FRP; FrzA; sFRP; SARP |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
