Species |
Human |
Protein Construction |
SMR3B (Gln23-Pro79)_x000D_ Accession # NP_006676.1 |
mFc (IgG1) |
N-term |
C-term |
|
Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
31.47 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
SMR3B (P-B, PRL3, PROL3), namely submaxillary gland androgen regulated protein 3B, is a proline-rich protein specifically expressed in salivary glands. The SMR3B is an 8.188 kilodalton protein that belongs to the gene family whose other members are SMR3A and PROL1, which all produce opiorphin homologs. It is predicted to enable endopeptidase inhibitor activity and be involved in cellular response to lipopolysaccharide. SMR3B also regulates pain perception. |
Synonyms |
PBII; PRL3; PROL3; P-B |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.