| Species |
Human |
| Protein Construction |
| His |
TENM2 (Gly401-Asn841)_x000D_
Accession # Q9NT68-1 |
| N-term |
C-term |
|
| Purity |
> 90% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1 EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
48.48 kDa |
| Apparent Molecular Weight |
The protein cleaved to 55-65 kDa, 38-43 kDa and 25-30 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22 μm filtered solution in PBS, 2 mM DTT (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control. |
| Synonyms |
Teneurin-2; Ten-2; Tenascin-M2; Ten-m2; KIAA1127; ODZ2; TNM2 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
