| Species |
Mouse |
| Protein Construction |
TREML2/TLT-2 (His25-Ala270)_x000D_
Accession # Q2LA85 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
28.6 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 73-80 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the susceptibility and pathogenesis of AD. |
| Synonyms |
TLT-2; C6orf76; dJ238O23.1; FLJ13693; MGC149715; MGC149716; TREML2; UNQ6268/PRO20473 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
