Species |
Rabbit |
Protein Construction |
Syndecan-1 (Leu23-Gly254)_x000D_ Accession # XP_008252990.1 |
His |
N-term |
C-term |
|
Purity |
> 90% as determined by BisTris PAGE > 90% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
24.57 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy. |
Synonyms |
Syndecan 1; SYND1; CD138; SDC; SDC1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.