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Scanning mutagenesis of the voltage-gated sodium channel Na12 using base editing
Authors: Juan Lorenzo B Pablo, Savannah L Cornett, Lei A Wang, Sooyeon Jo, Tobias Brünger, Nikita Budnik, Mudra Hegde, Jean-Marc DeKeyser, Christopher H Thompson, John G Doench, Dennis Lal, Alfred L George, Jen Q Pan
Journal: Cell Rep
PubMed ID: 38823014
Doi: 10.1016/j.celrep.2024.114327
Products & Services: Gene Synthesis   
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models
Authors: Xuesong Wang, Christopher A Cottrell, Xiaozhen Hu, Rashmi Ray, Maria Bottermann, Paula Maldonado Villavicencio, Yu Yan, Zhenfei Xie, John E Warner, Jordan Renae Ellis-Pugh, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Sergey Menis, Sebastian Rämisch, Saman Eskandarzade, Michael Kubitz, Ryan Tingle Nicole Phelps, Bettina Groschel, Sunny Himansu, Andrea Carfi, Kathrin H Kirsch, Stephanie R Weldon, Usha Nair, William R Schief, Facundo D Batista
Journal: Science immunology
PubMed ID: 38753808
Doi: 10.1126/sciimmunol.adn0622
Products & Services: Gene Synthesis   
Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
Authors: Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M O'Neill, Koji Yamanaka, S Samar Hasnain
Journal: Sci Rep
PubMed ID: 38802492
Doi: 10.1038/s41598-024-62903-5
Products & Services: Gene Synthesis   
Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL316 of herpes simplex virus 1
Authors: Akihisa Kato, Ryoji Iwasaki, Kousuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Tohru Natsume, Hideo Kusano, Shungo Adachi, Shuichi Kawano, Yasushi Kawaguchi
Journal: J Virol
PubMed ID: 38819171
Doi: 10.1128/jvi.00747-24
Products & Services: Gene Synthesis   
Analysis of the molecular basis for the non-amylolytic and non-proteolytic nature of Aspergillus vadensis CBS 113365
Authors: Dujuan Liu, Sandra Garrigues, Helena Culleton, Vincent A McKie, Ronald P de Vries
Journal: N Biotechnol
PubMed ID: 38697469
Doi: 10.1016/j.nbt.2024.04.003
Products & Services: Gene Synthesis   
CRISPR/Cas9-Mediated Knockout of the Lycopene ε-Cyclase for Efficient Astaxanthin Production in the Green Microalga
Authors: Jacob Sebastian Kneip, Niklas Kniepkamp, Junhwan Jang, Maria Grazia Mortaro, EonSeon Jin, Olaf Kruse, Thomas Baier
Journal: Plants (Basel)
PubMed ID: 38794462
Doi: 10.3390/plants13101393
Products & Services: PCR Cloning and Subcloning   Gene Synthesis   
Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments
Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy
Journal: Sci Rep
PubMed ID: 38773163
Doi: 10.1038/s41598-024-61566-6
Products & Services: Gene Synthesis   
Nanobody-based immunosensor for the detection of H pylori in saliva
Authors: Mohammad Ia Ahmad, Célia G Amorim, Luay F Abu Qatouseh, Maria C B S M Montenegro
Journal: Biosens Bioelectron
PubMed ID: 38810413
Doi: 10.1016/j.bios.2024.116423
Products & Services: Gene Synthesis   
Early Animal Origin of BACE1 APP/Aβ Proteolytic Function
Authors: James A Langeland, Lillian Baumann, Eva M DeYoung, Raphaela Angelina Varella, Nkatha Mwenda, Alejandro Aguirre, D Blaine Moore
Journal: Biology (Basel)
PubMed ID: 38785802
Doi: 10.3390/biology13050320
Products & Services: Gene Synthesis   
Three in one: An effective and universal vaccine expressing heterologous tandem RBD trimer by rabies virus vector protects mice against SARS-CoV-2
Authors: Jingbo Huang, Weiqi Wang, Hailun Li, Yujie Bai, Yumeng Song, Cuicui Jiao, Hongli Jin, Pei Huang, Haili Zhang, Xianzhu Xia, Feihu Yan, Yuanyuan Li, Hualei Wang
Journal: Antiviral Res
PubMed ID: 38740191
Doi: 10.1016/j.antiviral.2024.105905
Products & Services: Gene Synthesis   

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