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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex
Authors: Mandy S M Wan, Reyhan Muhammad, Marios G Koliopoulos, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri
Journal: nature communications
PubMed ID: 37137925
Doi: 10.1038/s41467-023-38276-0
Products & Services: Gene Synthesis   
MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity
Authors: Damodar Gullipalli, Takashi Miwa, Madhu Golla, Sayaka Sato, Sree Angampalli, Wen-Chao Song
Journal: J Immunol
PubMed ID: 36988282
Doi: 10.4049/jimmunol.2200932
Products & Services: Gene Synthesis   
Engineered ketocarotenoid biosynthesis in the polyextremophilic red microalga Cyanidioschyzon merolae 10D
Authors: Mark Seger , Fakhriyya Mammadova , Melany Villegas-Valencia , Barbara ´ Bastos de Freitas , Clarissa Chang , Iona Isachsen , Haley Hemstreet , Fatimah Abualsaud , Malia Boring , Peter J. Lammers , Kyle J. Lauersen
Journal: Metabolic Engineering Communications
Doi: 10.1016/j.mec.2023.e00226
Products & Services: Gene Synthesis   
Safety and Efficacy of Intravenous and Intrathecal Delivery of AAV9-Mediated ARSA in Minipigs
Authors: Aysilu Mullagulova , Alisa Shaimardanova , Valeriya Solovyeva , Yana Mukhamedshina , Daria Chulpanova , Alexander Kostennikov, Shaza Issa, Albert Rizvanov
Journal: Int J Mol Sci .
PubMed ID: 37298156
Doi: 10.3390/ijms24119204
Products & Services: Gene Synthesis   
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex
Authors: Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario J Borgnia, Robin E Stanley
Journal: Nat Struct Mol Biol
PubMed ID: 37231153
Doi: 10.1038/s41594-023-00991-z
Products & Services: Gene Synthesis   
In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g
Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova
Journal: bioRxiv .
PubMed ID: 37292671
Doi: 10.1101/gad.350829.123
Products & Services: Gene Synthesis   
A highly efficient transgene knock-in technology in clinically relevant cell types
Authors: Alexander G Allen, Samia Q Khan, Carrie M Margulies, Ramya Viswanathan, Swarali Lele, Laura Blaha, Sean N Scott, Kaitlyn M Izzo, Alexandra Gerew, Rithu Pattali, Nadire R Cochran, Carl S Holland, Amy H Zhao, Stephen E Sherman, Michael C Jaskolka, Meng Wu, Aaron C Wilson, Xiaoqi Sun, Dawn M Ciulla, Deric Zhang, Jacqueline D Nelson, Peisheng Zhang, Patrizia Mazzucato, Yan Huang, Georgia Giannoukos, Eugenio Marco, Michael Nehil, John A Follit, Kai-Hsin Chang, Mark S Shearman, Christopher J Wilson, John A Zuris
Journal: Nat Biotechnol
PubMed ID: 37127662
Doi: 10.1038/s41587-023-01779-8
Products & Services: Gene Synthesis   
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Authors: Nahye Kim, Sungchul Choi, Sungjae Kim, Myungjae Song, Jung Hwa Seo, Seonwoo Min, Jinman Park, Sung-Rae Cho, Hyongbum Henry Kim
Journal: Nat Biotechnol
PubMed ID: 37188916
Doi: 10.1038/s41587-023-01792-x
Products & Services: Gene Synthesis   
Structure of a 10-23 Deoxyribozyme Exhibiting a Homodimer Conformation
Authors: Evan Cramer, Sarah Starcovic, Rebekah Avey, Ali Kaya, Aaron Robart
Journal: Res Sq
PubMed ID: 37398199
Doi: 10.21203/rs.3.rs-2252941/v1
Products & Services: Gene Synthesis   
Inflammation Modifies miR-21 Expression Within Neuronal Extracellular Vesicles to Regulate Remyelination Following Spinal Cord Injury
Authors: Tianyu Han, Peiwen Song, Zuomeng Wu, Yunlei Liu, Wang Ying, Cailiang Shen
Journal: Stem Cell Rev Rep
PubMed ID: 37256514
Doi: 10.1007/s12015-023-10560-y
Products & Services: Gene Synthesis   

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