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Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement

Authors: Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M O'Neill, Koji Yamanaka, S Samar Hasnain

Journal: Sci Rep

PubMed ID: 38802492

Doi: 10.1038/s41598-024-62903-5

Products & Services: Gene Synthesis

Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis

Authors: Corine O Smith, Graham R Moran

Journal: Biochemistry

PubMed ID: 38691339

Doi: 10.1021/acs.biochem.4c00025

Products & Services: Gene Synthesis

Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL316 of herpes simplex virus 1

Authors: Akihisa Kato, Ryoji Iwasaki, Kousuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Tohru Natsume, Hideo Kusano, Shungo Adachi, Shuichi Kawano, Yasushi Kawaguchi

Journal: J Virol

PubMed ID: 38819171

Doi: 10.1128/jvi.00747-24

Products & Services: Gene Synthesis

CRISPR/Cas9-Mediated Knockout of the Lycopene ε-Cyclase for Efficient Astaxanthin Production in the Green Microalga

Authors: Jacob Sebastian Kneip, Niklas Kniepkamp, Junhwan Jang, Maria Grazia Mortaro, EonSeon Jin, Olaf Kruse, Thomas Baier

Journal: Plants (Basel)

PubMed ID: 38794462

Doi: 10.3390/plants13101393

Products & Services: PCR Cloning and Subcloning Gene Synthesis

Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments

Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy

Journal: Sci Rep

PubMed ID: 38773163

Doi: 10.1038/s41598-024-61566-6

Products & Services: Gene Synthesis

Nanobody-based immunosensor for the detection of H pylori in saliva

Authors: Mohammad Ia Ahmad, Célia G Amorim, Luay F Abu Qatouseh, Maria C B S M Montenegro

Journal: Biosens Bioelectron

PubMed ID: 38810413

Doi: 10.1016/j.bios.2024.116423

Products & Services: Gene Synthesis

Early Animal Origin of BACE1 APP/Aβ Proteolytic Function

Authors: James A Langeland, Lillian Baumann, Eva M DeYoung, Raphaela Angelina Varella, Nkatha Mwenda, Alejandro Aguirre, D Blaine Moore

Journal: Biology (Basel)

PubMed ID: 38785802

Doi: 10.3390/biology13050320

Products & Services: Gene Synthesis

Three in one: An effective and universal vaccine expressing heterologous tandem RBD trimer by rabies virus vector protects mice against SARS-CoV-2

Authors: Jingbo Huang, Weiqi Wang, Hailun Li, Yujie Bai, Yumeng Song, Cuicui Jiao, Hongli Jin, Pei Huang, Haili Zhang, Xianzhu Xia, Feihu Yan, Yuanyuan Li, Hualei Wang

Journal: Antiviral Res

PubMed ID: 38740191

Doi: 10.1016/j.antiviral.2024.105905

Products & Services: Gene Synthesis

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Authors: Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Journal: Front Pharmacol

PubMed ID: 38835669

Doi: 10.3389/fphar.2024.1392328

Products & Services: Gene Synthesis

Assessing the Impact of Novel Exon 11 Variants on Pre-mRNA Splicing

Authors: Halla Elshwekh, Inas M Alhudiri, Adam Elzagheid, Nabil Enattah, Yasmine Abbassi, Lubna Abou Assali, Ilenia Marino, Cristiana Stuani, Emanuele Buratti, Maurizio Romano

Journal: Cells

PubMed ID: 38786046

Doi: 10.3390/cells13100824

Products & Services: Gene Synthesis