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An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension

Authors: Elisabeth Fuchs, Imke Rudnik-Jansen, Anders Dinesen, Denis Selnihhin, Ole Aalund Mandrup, Kader Thiam, Jørgen Kjems, Finn Skou Pedersen, Kenneth A Howard

Journal: Acta Biomater

PubMed ID: 36162760

Doi: 10.1016/j.actbio.2022.09.048

Products & Services: Plasmid DNA Preparation

High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development

Authors: Shalev Gihaz, Peter Gareiss, Jae-Yeon Choi, Isaline Renard, Anasuya Chattopadhyay Pal, Yulia Surovsteva, Joy E Chiu, Jose Thekkiniath, Mark Plummer, William Hungerford, Micaela L Montgomery, Alanah Hosford, Emily M Adams, Jorge D Lightfoot, David Fox, Kayode K Ojo, Bart L Staker, Kevin Fuller, Choukri Ben Mamoun

Journal: Structure

PubMed ID: 36167065

Doi: 10.1016/j.str.2022.09.001

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Fluorescence Spectroscopy of Low-Level Endogenous β-Adrenergic Receptor Expression at the Plasma Membrane of Differentiating Human iPSC-Derived Cardiomyocytes

Authors: Philipp Gmach, Marc Bathe-Peters, Narasimha Telugu, Duncan C Miller, Paolo Annibale

Journal: Int J Mol Sci

PubMed ID: 36142320

Doi: 10.3390/ijms231810405

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Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies

Authors: J Sebastian Temme, Jennifer A Crainic, Laura M Walker, Weizhun Yang, Zibin Tan, Xuefei Huang, Jeffrey C Gildersleeve

Journal: J Biol Chem

PubMed ID: 36087840

Doi: 10.1016/j.jbc.2022.102468

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Autophagic flux restoration of senescent T cells improves antitumor activity of TCR-engineered T cells

Authors: Chaoting Zhang, Yizhe Sun, Shance Li, Luyan Shen, Xia Teng, Yefei Xiao, Ping Zhou, Zheming Lu

Journal: Clin Transl Immunology

PubMed ID: 36188121

Doi: 10.1002/cti2.1419

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De Novo design of a humanized antiCD33 antibody-oridonin conjugate for acute myeloid leukemia therapy

Authors: Hui Feng, Yi Liu, Mengyao Zhang, Ruimin Liu, Jincheng Wang, Wenjuan Wang, Pengcheng He, Penghui Zhang, Fan Niu

Journal: Biochem Biophys Res Commun

PubMed ID: 36122452

Doi: 10.1016/j.bbrc.2022.09.032

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Evidence of Orientation-Dependent Early States of Prion Protein Misfolded Structures from Single Molecule Force Spectroscopy

Authors: Andrea Raspadori, Valentina Vignali, Anna Murello, Gabriele Giachin, Bruno Samorì, Motomasa Tanaka, Carlos Bustamante, Giampaolo Zuccheri, Giuseppe Legname

Journal: Biology (Basel)

PubMed ID: 36138837

Doi: 10.3390/biology11091358

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Dynamic Actin Filament Traps Mediate Active Diffusion of Vesicular Stomatitis Virus Ribonucleoproteins

Authors: Steven J Moran, Shelby Puckett, David A Ornelles, Jed C Macosko, George Holzwarth, Douglas S Lyles

Journal: J Virol

PubMed ID: 36135365

Doi: 10.1128/jvi.00934-22

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Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells

Authors: Takayoshi Otsuka, Ho-Man Kan, Timothy D Mason, Lakshmi S Nair, Cato T Laurencin

Journal: Stem Cells Dev

PubMed ID: 35920108

Doi: 10.1089/scd.2022.0053

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Development and optimization of biologically contained Marburg virus for high-throughput antiviral screening

Authors: Bert Vanmechelen, Joren Stroobants, Winston Chiu, Lieve Naesens, Joost Schepers, Kurt Vermeire, Piet Maes

Journal: Antiviral Res

PubMed ID: 36183903

Doi: 10.1016/j.antiviral.2022.105426

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