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The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor

Authors: Francisco J Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E Shepard, Santiago Rodríguez de Córdoba, M Cristina Vega

Journal: Nat Commun

PubMed ID: 35413960

Doi: 10.1038/s41467-022-29580-2

Products & Services: Plasmid DNA Preparation

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Authors: Sachin Wani, Anna Daroszewska, Donald M Salter, Rob J van 't Hof, Stuart H Ralston, Omar M E Albagha

Journal: Dis Model Mech

PubMed ID: 35229101

Doi: 10.1242/dmm.049318

Products & Services: Plasmid DNA Preparation

A Nanopore Based Molnupiravir Sensor

Authors: Wendong Jia , Chengzhen Hu , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: ACS Sens

PubMed ID: 35427117

Doi: 10.1021/acssensors.2c00447

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Insect Cells for High-Yield Production of SARS-CoV-2 Spike Protein: Building a Virosome-Based COVID-19 Vaccine Candidate

Authors: Bárbara Fernandes, Rute Castro, Farien Bhoelan, Denzel Bemelman, Ricardo A Gomes, Júlia Costa, Patrícia Gomes-Alves, Toon Stegmann, Mario Amacker, Paula M Alves, Sylvain Fleury, António Roldão

Journal: Pharmaceutics

PubMed ID: 35456687

Doi: 10.3390/pharmaceutics14040854

Products & Services: Plasmid DNA Preparation

Gene Expression in a Humanized 21-Hydroxylase Mouse Model Does Not Affect Adrenocortical Morphology and Function

Authors: Tina Schubert, Nicole Reisch, Ronald Naumann, Ilka Reichardt, Dana Landgraf, Friederike Quitter, Shamini Ramkumar Thirumalasetty, Anne-Kristin Heninger, Mihail Sarov, Mirko Peitzsch, Angela Huebner, Katrin Koehler

Journal: J Endocr Soc

PubMed ID: 35592511

Doi: 10.1210/jendso/bvac062

Products & Services: Plasmid DNA Preparation

Glycoside hydrolase from the GH76 family indicates that marine Salegentibacter sp Hel_I_6 consumes alpha-mannan from fungi

Authors: Vipul Solanki, Karen Krüger, Conor J Crawford, Alonso Pardo-Vargas, José Danglad-Flores, Kim Le Mai Hoang, Leeann Klassen, D Wade Abbott, Peter H Seeberger, Rudolf I Amann, Hanno Teeling, Jan-Hendrik Hehemann

Journal: ISME J

PubMed ID: 35414716

Doi: 10.1038/s41396-022-01223-w

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A GH115 α-glucuronidase structure reveals dimerization-mediated substrate binding and a proton wire potentially important for catalysis

Authors: Casper Wilkens, Marlene Vuillemin, Bo Pilgaard, Igor Polikarpov, Jens Preben Morth

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35503213

Doi: 10.1107/S2059798322003527

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Mapping of molecular interactions between human E3 ligase TRIM69 and Dengue virus NS3 protease using hydrogen-deuterium exchange mass spectrometry

Authors: Tanaya Bagga, Nikhil Kumar Tulsian, Yu Keung Mok, R Manjunatha Kini, J Sivaraman

Journal: Cell Mol Life Sci

PubMed ID: 35397701

Doi: 10.1007/s00018-022-04245-x

Products & Services: Plasmid DNA Preparation

Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi

Authors: Yujie Yuan, Shu Cheng, Guangkai Bian, Pan Yan, Zhengning Ma, Wen Dai, Rong Chen, Shuai Fu, Huiwen Huang, Haoming Chi, Yousheng Cai, Zixin Deng & Tiangang Liu

Journal: Nature Catalysis

Doi: 10.1038/s41929-022-00762-x

Products & Services: Plasmid DNA Preparation

Hypericin nanoparticles for self-illuminated photodynamic cytotoxicity based on bioluminescence resonance energy transfer

Authors: Hao-Han Yu, Qiu-Ping Deng, Qing-Hua Zheng, Yi Wang, Jian Shen, Jia-Hong Zhou

Journal: Int J Pharm

PubMed ID: 35427744

Doi: 10.1016/j.ijpharm.2022.121738

Products & Services: Plasmid DNA Preparation

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