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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Access to Axially Chiral Biaryl Benzylamines via Ancestral Enzyme- Enabled Reductive Amination Desymmetrization

Authors: Wen-Qing, ZhengXin-Xin, ZhuZheng, ZhuTairan, YangLifen, ZhengRui, PanShenlin, WangLixin, ZhangQi, ChenJian-He, XuYongtao Xie, Yongtao Xie

Journal: ACS catalysis

Doi: 10.1021/acscatal.4c06881

Products & Services: Plasmid DNA Preparation

Structural insights into RNA cleavage by PIWI Argonaute

Authors: Zhiqing Li , Qikui Xu , Jing Zhong , Yan Zhang , Tianxiang Zhang , Xiaoze Ying , Xiaoli Lu , Xiaoyi Li , Li Wan , Junchao Xue , Jing Huang , Ying Zhen , Zhao Zhang， Jianping Wu , En-Zhi Shen

Journal: Nature

PubMed ID: 39814893

Doi: 10.1038/s41586-024-08438-1

Products & Services: Plasmid DNA Preparation

Developing orthogonal fluorescent RNAs for photoactive dual-color imaging of RNAs in live cells

Authors: Peng Yin , Chunzheng Huang , Li Zhang , Zhenzhen Li , Caijun Zhong , Shi Kuang , Chunyang Lei , Yan Huang , Zhou Nie

Journal: Angew Chem Int Ed Engl

PubMed ID: 39801450

Doi: 10.1002/anie.202424060

Products & Services: Plasmid DNA Preparation

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Authors: Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag & Euna Yoo

Journal: Nature Communications

PubMed ID: 39843430

Doi: 10.1038/s41467-025-56336-5

Products & Services: Plasmid DNA Preparation

Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction

Authors: Xin-Xin Zhu, Wen-Qing Zheng, Zi-Wei Xia, Xin-Ru Chen, Tian Jin, Xu-Wei Ding, Fei-Fei Chen, Qi Chen, Jian-He Xu, Xu-Dong Kong, Gao-Wei Zheng

Journal: Nat Commun

PubMed ID: 39609402

Doi: 10.1038/s41467-024-54613-3

Products & Services: Plasmid DNA Preparation

Identification of an RNA-binding perturbing characteristic for thiopurine drugs and their derivatives to disrupt CELF1–RNA interaction

Authors: Yang Tan , Zhibo Zhao , Qingfang Han , Peipei Xu , Xiaopeng Shen , Yajun Jiang , Qiang Xu , Xingxin Wu

Journal: Nucleic Acids Research

PubMed ID: 39268573

Doi: 10.1093/nar/gkae788

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Improvement and application of vacuum-infiltration system in tomato

Authors: Xinghao Yao, Ayat Taheri, Hang Liu, Yaojie Zhang, Ling Li, Jin Shao, Ke Wu, Qing Miao, Weizhi He, Xinyi Hu, Kexuan Tang

Journal: Horticulture research

Doi: doi.org/10.1093/hr/uhae197

Products & Services: Plasmid DNA Preparation

Structure and genome editing of type I-B CRISPR-Cas

Authors: Meiling Lu, Chenlin Yu, Yuwen Zhang, Wenjun Ju, Zhi Ye, Chenyang Hua, Jinze Mao, Chunyi Hu, Zhenhuang Yang & Yibei Xiao

Journal: Nat Commun

PubMed ID: 38750051

Doi: 10.1038/s41467-024-48598-2

Products & Services: Synthetic Guide RNA Plasmid DNA Preparation

CRISPR/Cas13a-based supersensitive circulating tumor DNA assay for detecting EGFR mutations in plasma

Authors: Li Wang , Xiaosha Wen , Yang Yang , Zheng Hu , Jing Jiang , Lili Duan , Xiaofen Liao , Yan He , Yaru Liu , Jing Wang , Zhikun Liang , Xiaoya Zhu , Quan Liu , Tiancai Liu , Dixian Luo

Journal: Commun Biol

PubMed ID: 38806596

Doi: 10.1038/s42003-024-06368-2

Products & Services: Plasmid DNA Preparation