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Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket
Authors: Johannes Morstein , Victoria Bowcut , Micah Fernando , Yue Yang , Lawrence Zhu , Meredith L Jenkins , John T Evans , Keelan Z Guiley , D Matthew Peacock , Sophie Krahnke , Zhi Lin , Katrine A Taran , Benjamin J Huang , Andrew G Stephen , John E Burke , Felice C Lightstone , Kevan M Shokat
Journal: Cell
PubMed ID: 39255801
Doi: 10.1016/j.cell.2024.08.017
Products & Services: DNA Sequencing   
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein
Authors: Wenjuan Du, Oliver Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch
Journal: Nat Commun
PubMed ID: 38909062
Doi: 10.1038/s41467-024-49693-0
Products & Services: DNA Sequencing   
Seeding activity of human superoxide dismutase 1 aggregates in familial and sporadic amyotrophic lateral sclerosis postmortem neural tissues by real-time quaking-induced conversion
Authors: Justin K. Mielke, Mikael Klingeborn, Eric P. Schultz, Erin L. Markham, Emily D. Reese, Parvez Alam, Ian R. Mackenzie, Cindy V. Ly, Byron Caughey, Neil R. Cashman & Moses J. Leavens
Journal: Acta Neuropathologica
PubMed ID: 38884646
Doi: 10.1007/s00401-024-02752-8
Products & Services: DNA Sequencing   
Deciphering Structural Traits for Thermal and Kinetic Stability Across Protein Family Evolution through Ancestral Sequence Reconstruction
Authors: Pablo A Cea, Myriam Pérez, Sixto M Herrera, Sebastián M Muñoz, Nicolás Fuentes-Ugarte, José Coche-Miranda, Pablo Maturana, Victoria Guixé, Victor Castro-Fernandez
Journal: Mol Biol Evol
PubMed ID: 38913681
Doi: 10.1093/molbev/msae127
Products & Services: DNA Sequencing   
The Gene Network That Regulates Head Organizer Activity in Is Differentially Regulated in Epidermis and Gastrodermis
Authors: Laura Iglesias Ollé, Chrystelle Perruchoud, Paul Gerald Layague Sanchez, Matthias Christian Vogg, Brigitte Galliot
Journal: Biomedicines
PubMed ID: 38927481
Doi: 10.3390/biomedicines12061274
Products & Services: DNA Sequencing   
Glycosyl transferase GT2 genes mediate the biosynthesis of an unusual (1,3;1,4)-β-glucan exopolysaccharide in the bacterium Sarcina ventriculi
Authors: Edwin R Lampugnani, Kris Ford, Yin Ying Ho, Allison van de Meene, Jelle Lahnstein, Hwei-Ting Tan, Rachel A Burton, Geoffrey B Fincher, Thomas Shafee, Antony Bacic, Jochen Zimmer, Xiaohui Xing, Vincent Bulone, Monika S Doblin, Eric M Roberts
Journal: Mol Microbiol
PubMed ID: 38750617
Doi: 10.1111/mmi.15276
Products & Services: DNA Sequencing   
Multifunctional bispecific nanovesicles targeting SLAMF7 trigger potent antitumor immunity
Authors: Manman Zhu, Yongjian Wu, Tianchuan Zhu, Jian Chen, Zhenxing Chen, Hanxi Ding, Siyi Tan, Jianzhong He, Qi Zeng, Xi Huang
Journal: Cancer Immunol Res
PubMed ID: 38819238
Doi: 10.1158/2326-6066.CIR-23-1102
Products & Services: DNA Sequencing   
Delivery of endolysin across outer membrane of Gram-negative bacteria using translocation domain of botulinum neurotoxin
Authors: Wonbeom Park, Myungseo Park, Jihwan Chun, Jaehyeon Hwang, Suhyun Kim, Nayoon Choi, Soo Min Kim, SeungJoo Kim, Sangwon Jung, Kwan Soo Ko, Dae-Hyuk Kweon
Journal: Int J Antimicrob Agents
PubMed ID: 38795926
Doi: 10.1016/j.ijantimicag.2024.107216
Products & Services: DNA Sequencing   
Radiation-primed TGF-β trapping by engineered extracellular vesicles for targeted glioblastoma therapy
Authors: Ruyu Liang, Hongyu Lu, Haifeng Zhu, Gaofeng Liang, Junxia Zhang, Jun Gao, Tian Tian
Journal: J Control Release
PubMed ID: 38740092
Doi: 10.1016/j.jconrel.2024.05.022
Products & Services: DNA Sequencing   
Two-point immobilization of M3 muscarinic receptor: a method for recognizing receptor antagonists in natural products
Authors: Xiaomin Huang, Ting Wang, Ludan Wang, Yantao Sun, Ziru Zhang, Yajun Zhang
Journal: BMC Chem
PubMed ID: 38702791
Doi: 10.1186/s13065-024-01198-z
Products & Services: DNA Sequencing   

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