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Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells

Authors: Wen-Hsin Sandy Lee, Zhiyong Ye, Alice M S Cheung, Y P Sharon Goh, Hsueh Ling Janice Oh, Ravisankar Rajarethinam, Siok Ping Yeo, Mun Kuen Soh, Esther Hian Li Chan, Lip Kun Tan, Soo-Yong Tan, Charles Chuah, Wee Joo Chng, John E Connolly, Cheng-I Wang

Journal: Mol Cancer Ther

PubMed ID: 34158344

Doi: 10.1158/1535-7163.MCT-20-0155

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A phase transition enhances the catalytic activity of SARM1, an NAD glycohydrolase involved in neurodegeneration

Authors: Heather S Loring, Victoria L Czech, Janneke D Icso, Lauren O'Connor, Sangram S Parelkar, Alexandra B Byrne, Paul R Thompson

Journal: Elife

PubMed ID: 34184985

Doi: 10.7554/eLife.66694

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Circular RNA TLK1 Promotes Sepsis-Associated Acute Kidney Injury by Regulating Inflammation and Oxidative Stress Through miR-106a-5p/HMGB1 Axis

Authors: Hai-Ping Xu, Xiao-Ying Ma, Chen Yang

Journal: Front Mol Biosci

PubMed ID: 34250012

Doi: 10.3389/fmolb.2021.660269

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Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring

Authors: Junfeng Chen, Huijuan Bi, Mats E Pettersson, Daiki X Sato, Angela P Fuentes-Pardo, Chunheng Mo, Shady Younis, Ola Wallerman, Patric Jern, Gregorio Molés, Ana Gómez, Gunnar Kleinau, Patrick Scheerer, Leif Andersson

Journal: Commun Biol

PubMed ID: 34172814

Doi: 10.1038/s42003-021-02307-7

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Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin

Authors: Ian A Durie, John V Dzimianski, Courtney M Daczkowski, Jack McGuire, Kay Faaberg, Scott D Pegan

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34196620

Doi: 10.1107/S205979832100509X

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The lncRNA PVT1 regulates autophagy in regulatory T cells to suppress heart transplant rejection in mice by targeting miR-146a

Authors: Jian Lu, Xiaodong Wang, Baotong Zhang, Peiyuan Li, Xuezhi Du, Feng Qi

Journal: Cell Immunol

PubMed ID: 34214903

Doi: 10.1016/j.cellimm.2021.104400

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Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection

Authors: Fouad S El-Mayet, Kelly S Harrison, Clinton Jones

Journal: Viruses

PubMed ID: 34203849

Doi: 10.3390/v13061148

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Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides

Authors: Bing Wang, Vladimir Svetlov, Yuri I Wolf, Eugene V Koonin, Evgeny Nudler, Irina Artsimovitch

Journal: MBio

PubMed ID: 34154407

Doi: 10.1128/mBio.01423-21

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A novel multiplexed Enzyme-Linked Immunosorbent Assay for the detection of IgG seroreactivity to cytomegalovirus (CMV) UL144

Authors: H Miller, P Simpson, M Forman, A Prigan, S Kehl, B Mesich, M Faron, N Ledeboer, R Arav-Boger

Journal: J Clin Microbiol

PubMed ID: 34076473

Doi: 10.1128/JCM.00964-21

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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Authors: Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula González-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, EunGi Kim, Xiaotian Zhang, Joshua M Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J H Ryan, Monica L Guzman, Jolanta Grembecka, Tomasz Cierpicki

Journal: Nat Chem Biol

PubMed ID: 34155404

Doi: 10.1038/s41589-021-00815-5

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