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Ameliorative effect of Alangium chinense (Lour) Harms on rheumatoid arthritis by reducing autophagy with targeting regulate JAK3-STAT3 and COX-2 pathways
Authors: Ting Xiao, Xingyan Cheng, Yuan Zhi, Fangfang Tian, Ai Wu, Feilong Huang, Ling Tao, Zhenghong Guo, Xiangchun Shen
Journal: J Ethnopharmacol
PubMed ID: 37690476
Doi: 10.1016/j.jep.2023.117133
Products & Services: Peptide Synthesis   
An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression
Authors: Qiong Luo , Yijun Liu , Ke Shi , Xuecheng Shen , Yaqi Yang , Xuejiao Liang , Liangliang Lu , Wenxuan Qiao , Airu Chen , Dongmei Hong , Yang Sun , Qiang Xu
Journal: Immunity
PubMed ID: 37473759
Doi: 10.1016/j.immuni.2023.06.012
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Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding
Authors: Ladan Khodaparast, Laleh Khodaparast, Guiqin Wu, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Teresa Garcia, Matthias De Vleeschouwer, Meine Ramakers, Hannah Wilkinson, Ramon Duran-Romaña, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz
Journal: Nat Commun
PubMed ID: 37689716
Doi: 10.1038/s41467-023-41191-z
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Nanopore sequencing of DNA-barcoded probes for highly multiplexed detection of microRNA, proteins and small biomarkers
Authors: Caroline Koch, Benedict Reilly-O'Donnell, Richard Gutierrez, Carla Lucarelli, Fu Siong Ng, Julia Gorelik, Aleksandar P Ivanov, Joshua B Edel
Journal: Nat Nanotechnol
PubMed ID: 37749222
Doi: 10.1038/s41565-023-01479-z
Products & Services: Peptide Synthesis   
Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling
Authors: Serena Vales, Jhanna Kryukova, Soumyanetra Chandra, Gintare Smagurauskaite, Megan Payne, Charlie J Clark, Katrin Hafner, Philomena Mburu, Stepan Denisov, Graham Davies, Carlos Outeiral, Charlotte M Deane, Garrett M Morris, Shoumo Bhattacharya
Journal: Nat Commun
PubMed ID: 37717048
Doi: 10.1038/s41467-023-41488-z
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Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection
Authors: Mark M Painter, Timothy S Johnston, Kendall A Lundgreen, Jefferson J S Santos, Juliana S Qin, Rishi R Goel, Sokratis A Apostolidis, Divij Mathew, Bria Fulmer, Justine C Williams, Michelle L McKeague, Ajinkya Pattekar, Ahmad Goode, Sean Nasta, Amy E Baxter, Josephine R Giles, Ashwin N Skelly, Laura E Felley, Maura McLaughlin, Joellen Weaver, Oliva Kuthuru, Jeanette Dougherty, Sharon Adamski, Sherea Long, Macy Kee, Cynthia Clendenin, Ricardo da Silva Antunes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alexander C Huang, Daniel J Rader, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry
Journal: Nat Immunol
PubMed ID: 37735592
Doi: 10.1038/s41590-023-01613-y
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An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses
Authors: Feifei Xiong, Chi Zhang, Baoyuan Shang, Mei Zheng, Qi Wang, Yahong Ding, Jian Luo, Xiuling Li
Journal: Emerg Microbes Infect
PubMed ID: 37671994
Doi: 10.1080/22221751.2023.2256422
Products & Services: Peptide Synthesis   
Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma
Authors: Chen Liang, Ting Wei, Ting Zhang, Chen Niu
Journal: Mol Med Rep
PubMed ID: 37772382
Doi: 10.3892/mmr.2023.13102
Products & Services: Peptide Synthesis   
Genome characterization of the novel lytic phage vB_AbaAut_ChT04 and the antimicrobial activity of its lysin peptide against Acinetobacter baumannii isolates from different time periods
Authors: Udomluk Leungtongkam, Thawatchai Kitti, Supat Khongfak, Rapee Thummeepak, Kannipa Tasanapak, Jintana Wongwigkarn, Sophit Khanthawong, Aouatif Belkhiri, Henrique G Ribeiro, John S Turner, Danish J Malik, Sutthirat Sitthisak
Journal: Arch Virol
PubMed ID: 37660314
Doi: 10.1007/s00705-023-05862-y
Products & Services: Peptide Synthesis   
Discovery of ACE Inhibitory Peptides Derived from Green Coffee Using In Silico and In Vitro Methods
Authors: Haopeng Dai, Min He, Guilin Hu, Zhongrong Li, Abdulbaset Al-Romaima, Zhouwei Wu, Xiaocui Liu, Minghua Qiu
Journal: Foods
PubMed ID: 37761189
Doi: 10.3390/foods12183480
Products & Services: Peptide Synthesis   

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