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Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment
Authors: Robin M Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter Bayliss, Olga Egorova, Almudena Neva-Alejo, Aj Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia Giblin, Joan Seoane
Journal: Clin Cancer Res
PubMed ID: 36441800
Doi: 10.1158/1078-0432.CCR-21-1888
Products & Services: Peptide Synthesis   
Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy
Authors: Natalia Plewa, Lucia Poncette, Thomas Blankenstein
Journal: J Immunother Cancer
PubMed ID: 36822673
Doi: 10.1136/jitc-2022-006001
Products & Services: Peptide Synthesis   
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy
Authors: Yaping Wu, Xiaowei Chang, Guizhu Yang, Li Chen, Qi Wu, Jiamin Gao, Ran Tian, Wenyun Mu, John Justin Gooding, Xin Chen, Shuyang Sun
Journal: Adv Mater
PubMed ID: 36656993
Doi: 10.1002/adma.202210787
Products & Services: Peptide Synthesis   
Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations
Authors: Joseph H Garcia, Erin A Akins, Saket Jain, Kayla J Wolf, Jason Zhang, Nikita Choudhary, Meeki Lad, Poojan Shukla, Sabraj Gill, Will Carson, Luis Carette, Allison Zheng, Sanjay Kumar, Manish K Aghi
Journal: biorxiv
PubMed ID: 36865128
Doi: 10.1101/2023.02.23.529575
Products & Services: Peptide Synthesis   
Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
Authors: Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Ctirad Hofr, Libor Macurek
Journal: Nucleic Acids Res
PubMed ID: 36651296
Doi: 10.1093/nar/gkac1269
Products & Services: Peptide Synthesis   
A natriuretic peptide molecule from Vigna angularis, VaEG45, confers rust resistance by inhibiting fungal development
Authors: Weina Sun , Mengqi Yuan , Lihua Yin , Xiwang Ke , Yuhu Zuo
Journal: Plant Cell Rep .
PubMed ID: 36576553
Doi: 10.1007/s00299-022-02967-7
Products & Services: Peptide Synthesis   
A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome
Authors: Soo Jung Lee , Xiaojie Zhang , Gang Xu , Jimo Borjigin , Michael M Wang
Journal: J Biol Chem .
PubMed ID: 36470429
Doi: 10.1016/j.jbc.2022.102772
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Authors: Saskia Meyer , Isaac Blaas , Ravi Chand Bollineni , Marina Delic-Sarac , Trung T Tran , Cathrine Knetter , Ke-Zheng Dai , Torfinn Støve Madssen , John T Vaage , Alice Gustavsen , Weiwen Yang , Lise Sofie Haug Nissen-Meyer , Karolos Douvlataniotis , Maarja Laos , Morten Milek Nielsen , Bernd Thiede , Arne Søraas , Fridtjof Lund-Johansen , Even H Rustad, Johanna Olweus
Journal: Cell Rep .
PubMed ID: 36656713
Doi: 10.1016/j.celrep.2023.111995
Products & Services: Peptide Synthesis   
Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance
Authors: Dario Gerace, Quan Zhou, Jennifer Hyoje-Ryu Kenty, Adrian Veres, Elad Sintov, Xi Wang, Kyle R Boulanger, Hongfei Li, Douglas A Melton
Journal: Cell Rep Med
PubMed ID: 36599351
Doi: 10.1016/j.xcrm.2022.100879
Products & Services: Peptide Synthesis   
Low-cost and prototype-friendly method for biocompatible encapsulation of implantable electronics with epoxy overmolding, hermetic feedthroughs and P3HT coating
Authors: Marek Novák, Jozef Rosina, Hana Bendová, Kristina Kejlová, Alena Vlková, Marian Rucki, Lada Svobodová, Robert Gürlich, Jan Hajer
Journal: Sci Rep
PubMed ID: 36717683
Doi: 10.1038/s41598-023-28699-6
Products & Services: Peptide Synthesis   

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