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SARS-CoV-2 variant B.1.1.7 caused HLA-A2 CD8 T cell epitope mutations for impaired cellular immune response.
Authors: Chanchan Xiao, Lipeng Mao , Zhigang Wang , Lijuan Gao , Guodong Zhu , Jun Su , Xiongfei Chen , Jun Yuan , Yutian Hu, Zhinan Yin, Jun Xie , Weiqing Ji , Haitao Niu , Feng Gao, Oscar Junhong Luo , Lianbo Xiao , Pengcheng Wang , Guobing Chen
Journal: iScience
PubMed ID: 35194575
Doi: 10.1016/j.isci.2022.103934
Products & Services: Peptide Synthesis   
Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants
Authors: Noemia S Lima, Maryam Mukhamedova, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P Black, Sijy O'Dell, Stephen D Schmidt, Damee Moon, Cynthia G Lorang, Bingchun Zhao, Man Chen, Kristin L Boswell, Jesmine Roberts-Torres, Rachel L Davis, Lowrey Peyton, Sandeep R Narpala, Sarah O'Connell, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J Ruckwardt, Amarendra Pegu, John Misasi, Nicole A Doria-Rose, Martin Gaudinski, Richard A Koup, Peter D Kwong, Adrian B McDermott, Sharon Amit, Timothy W Schacker, Itzchak Levy, John R Mascola, Nancy J Sullivan, Chaim A Schramm, Daniel C Douek
Journal: biorxiv
PubMed ID: 35378757
Doi: 10.1101/2022.03.28.486152
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In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes
Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte
Journal: Biophys J
PubMed ID: 35278426
Doi: 10.1016/j.bpj.2022.03.009
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Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization
Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker
Journal: Nat Struct Mol Biol
PubMed ID: 35347313
Doi: 10.1038/s41594-022-00749-z
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Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Authors: Jon Riise, Saskia Meyer, Isaac Blaas, Adity Chopra, Trung T Tran, Marina Delic-Sarac, Malu Lian Hestdalen, Ellen Brodin, Even Holth Rustad, Ke-Zheng Dai, John Torgils Vaage, Lise Sofie Haug Nissen-Meyer, Fredrik Sund, Karin F Wader, Anne T Bjornevik, Peter A Meyer, Gro O Nygaard, Marton König, Sigbjørn Smeland, Fridtjof Lund-Johansen, Johanna Olweus, Arne Kolstad
Journal: Br J Haematol
PubMed ID: 35254660
Doi: 10.1111/bjh.18149
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Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury
Authors: Wei Jiang, Pei Zhang, Peng Yang, Na Kang, Junqiang Liu, Yilixiati Aihemaiti, Haijun Tu
Journal: Mol Cell Proteomics
PubMed ID: 35257887
Doi: 10.1016/j.mcpro.2022.100222
Products & Services: Peptide Synthesis   
Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope
Authors: Adva Mechaly, Eran Diamant, Ron Alcalay, Alon Ben David, Eyal Dor, Amram Torgeman, Ada Barnea, Meni Girshengorn, Lilach Levin, Eyal Epstein, Ariel Tennenhouse, Sarel J Fleishman, Ran Zichel, Ohad Mazor
Journal: Antibodies (Basel)
PubMed ID: 35323195
Doi: 10.3390/antib11010021
Products & Services: Peptide Synthesis   
Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling
Authors: Maricel Gomez-Soler, Marina P. Gehring, Bernhard C. Lechtenberg,Elmer Zapata-Mercado, Alyssa Ruelos,Mike W. Matsumoto,Kalina Hristova,and Elena B. Pasquale
Journal: iScience
Doi: doi.org/10.1016/j.isci.2022.103870
Products & Services: Peptide Synthesis   
Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression
Authors: Yvonne E Smith, Guannan Wang, Ciara L Flynn, Stephen F Madden, Owen MacEneaney, Rodrigo G B Cruz, Cathy E Richards, Hanne Jahns, Marian Brennan, Mattia Cremona, Bryan T Hennessy, Katherine Sheehan, Alexander Casucci, Faizah A Sani, Lance Hudson, Joanna Fay, Sri H Vellanki, Siobhan O'Flaherty, Marc Devocelle, Arnold D K Hill, Kieran Brennan, Saraswati Sukumar, Ann M Hopkins
Journal: Cancers (Basel)
PubMed ID: 35267611
Doi: 10.3390/cancers14051303
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Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules
Authors: Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase
Journal: Sci Adv
PubMed ID: 35245125
Doi: 10.1126/sciadv.abj9867
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