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Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain-based vaccine candidate, RBD219-N1C1
Authors: Jungsoon Lee, Zhuyun Liu, Wen-Hsiang Chen, Junfei Wei, Rakhi Kundu, Rakesh Adhikari, Joanne Altieri Rivera, Portia M Gillespie, Ulrich Strych, Bin Zhan, Peter J Hotez, Maria Elena Bottazzi
Journal: Appl Microbiol Biotechnol
PubMed ID: 33959781
Doi: 10.1007/s00253-021-11281-3
Products & Services: Mammalian Expression   
Delayed production of neutralizing antibodies correlates with fatal COVID-19
Authors: Carolina Lucas, Jon Klein, Maria E Sundaram, Feimei Liu, Patrick Wong, Julio Silva, Tianyang Mao, Ji Eun Oh, Subhasis Mohanty, Jiefang Huang, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Benjamin Israelow, Chantal B F Vogels, M Catherine Muenker, C-Hong Chang, Arnau Casanovas-Massana, Adam J Moore, Joseph Zell, John B Fournier, Anne L Wyllie, Melissa Campbell, Alfred Lee, Hyung J Chun, Nathan D Grubaugh, Wade L Schulz, Shelli Farhadian, Charles Dela Cruz, Aaron M Ring, Albert C Shaw, Adam V Wisnewski, Inci Yildirim, Albert I Ko, Saad Omer, Akiko Iwasaki
Journal: Nat Med
PubMed ID: 33953384
Doi: 10.1038/s41591-021-01355-0
Products & Services: Mammalian Expression   
Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection
Authors: Taylor B Engdahl, Natalia A Kuzmina, Adam J Ronk, Chad E Mire, Matthew A Hyde, Nurgun Kose, Matthew D Josleyn, Rachel E Sutton, Apoorva Mehta, Rachael M Wolters, Nicole M Lloyd, Francisca R Valdivieso, Thomas G Ksiazek, Jay W Hooper, Alexander Bukreyev, James E Crowe
Journal: Cell Rep
PubMed ID: 33951434
Doi: 10.1016/j.celrep.2021.109086
Products & Services: Mammalian Expression   
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
Authors: Ugur Sahin, Alexander Muik, Isabel Vogler, Evelyna Derhovanessian, Lena M Kranz, Mathias Vormehr, Jasmin Quandt, Nicole Bidmon, Alexander Ulges, Alina Baum, Kristen E Pascal, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Peter Koch, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Manuel Tonigold, Carsten Boesler, Corinna Rosenbaum, Ludwig Heesen, Marie-Cristine Kühnle, Asaf Poran, Jesse Z Dong, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Tania Palanche, Armin Schultz, Sybille Baumann, Azita J Mahiny, Gábor Boros, Jonas Reinholz, Gábor T Szabó, Katalin Karikó, Pei-Yong Shi, Camila Fontes-Garfias, John L Perez, Mark Cutler, David Cooper, Christos A Kyratsous, Philip R Dormitzer, Kathrin U Jansen, Özlem Türeci
Journal: Nature
PubMed ID: 34044428
Doi: 10.1038/s41586-021-03653-6
Products & Services: Mammalian Expression   
Ovalbumin Antigen-Specific Activation of Human T Cell Receptor Closely Resembles Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics.
Authors: Chua XY,Salomon A
Journal: Journal of proteome research
PubMed ID: 34018748
Doi: 10.1021/acs.jproteome.1c00239
Products & Services: Mammalian Expression   
Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms
Authors: Xiaojie Shi, Yue Wan, Nan Wang, Jiangchao Xiang, Tao Wang, Xiaofeng Yang, Ju Wang, Xuxue Dong, Liang Dong, Lei Yan, Yu Li, Lili Liu, Shinchen Hou, Zhenwei Zhong, Ian A Wilson, Bei Yang, Guang Yang, Richard A Lerner
Journal: Nat Commun
PubMed ID: 33953162
Doi: 10.1038/s41467-021-22810-z
Products & Services: Mammalian Expression   
NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium
Authors: Caini Fan, Laureano D Asico, Van Anthony M Villar, Jessica Hunt, Santiago Cuevas, Ines Armando, Pedro A Jose, Prasad R Konkalmatt
Journal: Int J Mol Sci
PubMed ID: 33921209
Doi: 10.3390/ijms22083951
Products & Services: Mammalian Expression   
Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses
Authors: Estela Núñez-Manchón, Martí Farrera-Sal, Marc Otero-Mateo, Giancarlo Castellano, Rafael Moreno, David Medel, Ramon Alemany, Eneko Villanueva, Cristina Fillat
Journal: NAR Cancer
PubMed ID: 34316705
Doi: 10.1093/narcan/zcab015
Products & Services: Mammalian Expression   
Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke
Authors: Diana Mayor-Nunez, Zhanxin Ji, Xiujun Sun, Lucy Teves, J David Garman, Michael Tymianski
Journal: Sci Transl Med
PubMed ID: 33827973
Doi: 10.1126/scitranslmed.abb1498
Products & Services: Mammalian Expression   
FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling
Authors: Huang-Ming Chang, Kang-Yung Peng, Chieh-Kai Chan, Chiao-Yin Sun, Ying-Ying Chen, Han-Mei Chang, Chun-Lin Huang, Pei-Chun Liu, Peng-Ying Chen, Kuo-Chuan Wang, Wei-Jie Wang, Chen-Chi Wu, Yu-Feng Lin, Tai-Shuan Lai, Tao-Min Huang, Guang-Huar Young, Shuei-Liong Lin, Marlies Ostermann, Tzong-Shinn Chu, Jeff S Chueh, Vin-Cent Wu
Journal: Cell Death Dis
PubMed ID: 33866326
Doi: 10.1038/s41419-021-03693-w
Products & Services: Mammalian Expression   

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