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Therapeutic Targeting of Golgi Phosphoprotein 2 (GOLPH2) with Armed Antibodies: A Preclinical Study of Anti-GOLPH2 Antibody Drug Conjugates in Lung and Colorectal Cancer Models of Patient Derived Xenografts (PDX).

Authors: Liewen Heike，Markuly Norbert，L?ubli Heinz，Liu Yang，Matter Matthias S，Liewen Nora，Renner Christoph，Zippelius Alfred，Stenner F

Journal: Target Oncol

PubMed ID: 31541350

Doi: 10.1007/s11523-019-00667-z

Products & Services: Nucleic Acid Purification & Analysis

Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species.

Authors: Ng Andrew Ying Hui，Li Ziqing，Jones Megan M，Yang Shuting，Li Chunyi，Fu Chuanyun，Tu Chengjian，Oursler Merry Jo，Qu Jun，Yang Shu

Journal: Elife

PubMed ID: 31490121

Doi: 10.7554/eLife.42951

Products & Services: Nucleic Acid Purification & Analysis

Silencing of MALAT1 inhibits migration and invasion by sponging miR‑1‑3p in prostate cancer cells.

Authors: Dai Xiaofan，Liang Zuowen，Liu Lingyun，Guo Kaimin，Xu Shengqi，Wang Hongl

Journal: Mol Med Rep

PubMed ID: 31485645

Doi: 10.3892/mmr.2019.10602

Products & Services: Nucleic Acid Purification & Analysis

Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.

Authors: ShragaAmit，OlshvangEvgenia，DavidzohnNatalia，KhoshkenarPayam，GermainNicolas，ShurrushKhriesto，CarvalhoSilvia，AvramLiat，AlbeckShira，UngerTamar，LefkerBruce，SubramanyamChakrapani，HudkinsRobert L，MitchellAmir，ShulmanZiv，KinoshitaTakayoshi，Londo

Journal: Cell Chem Biol

PubMed ID: 30449673

Doi: 10.1016/j.chembiol.2018.10.011

Products & Services: Nucleic Acid Purification & Analysis

Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria.

Authors: Zhao J, Honda Y, Tanaka T, Hashimoto Y, Matsumoto N.

Journal: Materials (Basel)

PubMed ID: 31878096

Doi: 10.3390/ma13010095

Products & Services: Nucleic Acid Purification & Analysis

Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties.

Authors: Hörner M,,, Raute K,,, Hummel B,, Madl J,, Creusen G,, Thomas OS,,, Christen EH, Hotz N,, Gübeli RJ,, Engesser R,, Rebmann B, Lauer J,, Rolauffs B, Timmer J,, Schamel WWA,,,, Pruszak J,, Römer W,,,, Zurbriggen MD, Friedrich C, Walther A,,, Minguet S,,,, Sawarkar R,, Weber W,,.

Journal: Adv Mater

PubMed ID: 30687975

Products & Services: Nucleic Acid Purification & Analysis

Identification of IL-27 as potent regulator of inflammatory osteolysis associated with vitamin E-blended ultra-high molecular weight polyethylene debris of orthopedic implants.

Authors: Terkawi MA, Kadoya K, Takahashi D, Tian Y, Hamasaki M, Matsumae G, Alhasan H, Elmorsy S, Uetsuki K, Onodera T, Takahata M, Iwasaki N.

Journal: Acta Biomater

PubMed ID: 30880234

Products & Services: Nucleic Acid Purification & Analysis

Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly(ethylene glycol) hydrogels.

Authors: Amer LD, Saleh LS, Walker C, Thomas S, Janssen WJ, Alper S, Bryant SJ.

Journal: Acta Biomater

PubMed ID: 31568879