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In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei

Authors: Abhishek Dey, Anais Monroy-Eklund, Kaitlin Klotz, Arpita Saha, Justin Davis, Bibo Li, Alain Laederach, Kausik Chakrabarti

Journal: Nucleic Acids Res

PubMed ID: 34850114

Doi: 10.1093/nar/gkab1042

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High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

Authors: Julia R Port, Danielle R Adney, Benjamin Schwarz, Jonathan E Schulz, Daniel E Sturdevant, Brian J Smith, Victoria A Avanzato, Myndi G Holbrook, Jyothi N Purushotham, Kaitlin A Stromberg, Ian Leighton, Catharine M Bosio, Carl Shaia, Vincent J Munster

Journal: Viruses

PubMed ID: 34960775

Doi: 10.3390/v13122506

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Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial

Authors:

Journal: Lancet Infect Dis

PubMed ID: 34953520

Doi: 10.1016/S1473-3099(21)00751-9

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Study protocol for a randomised clinical trial of a decision aid and values clarification method for parents of a fetus or neonate diagnosed with a life-threatening congenital heart defect

Authors: Rebecca K Delaney, Nelangi M Pinto, Elissa M Ozanne, Louisa A Stark, Mandy L Pershing, Alistair Thorpe, Holly O Witteman, Praveen Thokala, Linda M Lambert, Lisa M Hansen, Tom H Greene, Angela Fagerlin

Journal: BMJ Open

PubMed ID: 34893487

Doi: 10.1136/bmjopen-2021-055455

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BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk

Authors: Qing-Tao Meng, Xian-Yu Liu, Xue-Ting Liu, Juan Liu, Admire Munanairi, Devin M Barry, Benlong Liu, Hua Jin, Yu Sun, Qianyi Yang, Fang Gao, Li Wan, Jiahang Peng, Jin-Hua Jin, Kai-Feng Shen, Ray Kim, Jun Yin, Ailin Tao, Zhou-Feng Chen

Journal: Elife

PubMed ID: 34919054

Doi: 10.7554/eLife.71689

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The key regulator LcERF056 enhances salt tolerance by modulating reactive oxygen species-related genes in Lotus corniculatus

Authors: Dan Wang, Zhanmin Sun, Xinxu Hu, Junbo Xiong, Lizhen Hu, Yuandong Xu, Yixiong Tang, Yanmin Wu

Journal: BMC Plant Biol

PubMed ID: 34965872

Doi: 10.1186/s12870-021-03336-4

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Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Authors: Lihong Liu, Sho Iketani, Yicheng Guo, Jasper F-W Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj S Nair, Jian Yu, Kenn K-H Chik, Terrence T-T Yuen, Chaemin Yoon, Kelvin K-W To, Honglin Chen, Michael T Yin, Magdalena E Sobieszczyk, Yaoxing Huang, Harris H Wang, Zizhang Sheng, Kwok-Yung Yuen, David D Ho

Journal: Nature

PubMed ID: 35016198

Doi: 10.1038/s41586-021-04388-0

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Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors

Authors: Ru Dong, Cheng Zhang, Chao Wang, Xin Zhou, Wen Li, Jin-Yang Zhang, Min Wang, Yong Xu, Li-Ping Sun

Journal: Bioorg Med Chem

PubMed ID: 34999525

Doi: 10.1016/j.bmc.2021.116592

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The Retropepsin-Type Protease APRc as a Novel Ig-Binding Protein and Moonlighting Immune Evasion Factor of

Authors: Pedro Curto, Andreia Barro, Carla Almeida, Ricardo S Vieira-Pires, Isaura Simões

Journal: MBio

PubMed ID: 34872352

Doi: 10.1128/mBio.03059-21

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The WalR-WalK signaling pathway modulates the activities of both CwlO and LytE through control of the peptidoglycan deacetylase PdaC in

Authors: Genevieve S Dobihal, Josué Flores-Kim, Ian J Roney, Xindan Wang, David Z Rudner

Journal: J Bacteriol

PubMed ID: 34871030

Doi: 10.1128/JB.00533-21

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