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Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism
Authors: Mattia Deluigi, Alexander Klipp, Christoph Klenk, Lisa Merklinger, Stefanie A Eberle, Lena Morstein, Philipp Heine, Peer R E Mittl, Patrick Ernst, Theodore M Kamenecka, Yuanjun He, Santiago Vacca, Pascal Egloff, Annemarie Honegger, Andreas Plückthun
Journal: Sci Adv
PubMed ID: 33571132
Doi: 10.1126/sciadv.abe5504
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Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain
Authors: Xuxiao Zhang, Juan Pu, Yipeng Sun, Bi Yuhai, Zhimin Jiang, Guanlong Xu, Hongyu Zhang, Jing Cao, Kin-Chow Chang, Jinhua Liu, Honglei Sun
Journal: J Virol
PubMed ID: 33408179
Doi: 10.1128/JVI.01272-20
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Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels
Authors: Jeffrey R McArthur, Nehan R Munasinghe, Rocio K Finol-Urdaneta, David J Adams, Macdonald J Christie
Journal: Front Pharmacol
PubMed ID: 33584315
Doi: 10.3389/fphar.2020.633679
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Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis
Authors: Chen Z, Luo J, Li J, Kim G, Stewart A, Urban JF Jr, Huang Y, Chen S, Wu LG, Chesler A, Trinchieri G, Li W, Wu C
Journal: Immunity
PubMed ID: 33220232
Doi: 10.1016/j.immuni.2020.10.014
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The role of Nrf2 in mitigating cadmium-induced oxidative stress of Marsupenaeus japonicus
Authors: Ren X, Xu Y, Yu Z, Mu C, Liu P, Li J
Journal: Environmental pollution (Barking, Essex : 1987)
PubMed ID: 33272803
Doi: 10.1016/j.envpol.2020.116112
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Lobaplatin Enhances Radioactive I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway
Authors: Jia-Hui Rong, Dong Li, Yu-Liang Li
Journal: Onco Targets Ther
PubMed ID: 33469307
Doi: 10.2147/OTT.S288012
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A novel and sensitive real-time PCR system for universal detection of poxviruses
Authors: Léa Luciani, Lucia Inchauste, Olivier Ferraris, Rémi Charrel, Antoine Nougairède, Géraldine Piorkowski, Christophe Peyrefitte, Stéphane Bertagnoli, Xavier de Lamballerie, Stéphane Priet
Journal: Sci Rep
PubMed ID: 33469067
Doi: 10.1038/s41598-021-81376-4
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Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3
Authors: Anderson SE, Longbotham JE, O'Kane PT, Ugur FS, Fujimori DG, Mrksich M
Journal: ACS Chemical Biology
PubMed ID: 33314922
Doi: 10.1021/acschembio.0c00891
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Competition of Ligands and the 18-mer Binding Domain of the RHAU Helicase for G-Quadruplexes: Orthosteric or Allosteric Binding Mechanism?
Authors: Marchand A, Beauvineau C, Teulade-Fichou MP, Zenobi R
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
PubMed ID: 33617136
Doi: 10.1002/chem.202004040
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CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons
Authors: Yang Y, Wen J, Zheng B, Wu S, Mao Q, Liang L, Li Z, Bachmann T, Bekker A, Tao YX
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
PubMed ID: 33051852
Doi: 10.1007/s13311-020-00931-5
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