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BT8009; a Nectin-4 targeting Bicycle® Toxin Conjugate for treatment of solid tumors
Authors: Michael Rigby, Gavin Bennett, Liuhong Chen, Gemma E Mudd, Helen Harrison, Paul J Beswick, Katerine van Rietschoten, Sophie M Watcham, Heather S Scott, Amy N Brown, Peter U Park, Carly Campbell, Eric Haines, Johanna Lahdenranta, Michael J Skynner, Phil Jeffrey, Nicholas Keen, Kevin Lee
Journal: Mol Cancer Ther
PubMed ID: 36112771
Doi: 10.1158/1535-7163.MCT-21-0875
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Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties
Authors: Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong Ong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36067305
Doi: 10.1073/pnas.2204179119
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A novel delayed lateral flow immunoassay for enhanced detection of SARS-CoV-2 spike antigen
Authors: Pawanrat Srithong, Sudkate Chaiyo, Ekawat Pasomsub, Sirirat Rengpipat, Orawon Chailapakul, Narong Praphairaksit
Journal: Mikrochim Acta
PubMed ID: 36125616
Doi: 10.1007/s00604-022-05467-3
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PpZAT10 negatively regulates peach cold resistance predominantly mediated by inhibiting VIN activity
Authors: YiChen ,JiachangSun ,YingyingWei ,KefengCao ,ShuJiang ,XingfengShao
Journal: Postharvest Biology and Technology
Doi: 10.1016/j.postharvbio.2022.111952
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Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile
Authors: Susan M Bueno, Katia Abarca, Pablo A González, Nicolás M S Gálvez, Jorge A Soto, Luisa F Duarte, Bárbara M Schultz, Gaspar A Pacheco, Liliana A González, Yaneisi Vázquez, Mariana Ríos, Felipe Melo-González, Daniela Rivera-Pérez, Carolina Iturriaga, Marcela Urzúa, Angélica Domínguez, Catalina A Andrade, Roslye V Berríos-Rojas, Gisela Canedo-Marroquín, Camila Covián, Daniela Moreno-Tapia, Farides Saavedra, Omar P Vallejos, Paulina Donato, Pilar Espinoza, Daniela Fuentes, Marcela González, Paula Guzmán, Paula Muñoz Venturelli, Carlos M Pérez, Marcela Potin, Álvaro Rojas, Rodrigo A Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Aarón Oyarzún-Arrau, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alessandro Sette, Gang Zeng, Weining Meng, José V González-Aramundiz, Alexis M Kalergis
Journal: Clin Infect Dis
PubMed ID: 34537835
Doi: 10.1093/cid/ciab823
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Extracellular expression of 's L-asparaginase II in results in novel enzyme with better parameters
Authors: Henrique P Biasoto, Cristina B Hebeda, Sandra H P Farsky, Adalberto Pessoa, Tales A Costa-Silva, Gisele Monteiro
Journal: Prep Biochem Biotechnol
PubMed ID: 35981094
Doi: 10.1080/10826068.2022.2111582
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Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain
Authors: Jing-Yi Zhou, Rui-Rui Yang, Jie Chang, Jia Song, Zi-Sheng Fan, Ying-Hui Zhang, Cheng-Hao Lu, Hua-Liang Jiang, Ming-Yue Zheng, Su-Lin Zhang
Journal: Acta Pharmacol Sin
PubMed ID: 35918411
Doi: 10.1038/s41401-022-00936-0
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Sall4 guides p53-mediated enhancer interference upon DNA damage in mouse embryonic stem cells
Authors: Lei Wang, Xiaojun Tan, Lu Chen, Sisi Xu, Weiping Huang, Nan Chen, Yizhou Wu, Chunyan Wang, Daqiang Zhou, Mangmang Li
Journal: Stem Cells
PubMed ID: 35977539
Doi: 10.1093/stmcls/sxac058
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Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses
Authors: Jeroen M J Tas, Ja-Hyun Koo, Ying-Cing Lin, Zhenfei Xie, Jon M Steichen, Abigail M Jackson, Blake M Hauser, Xuesong Wang, Christopher A Cottrell, Jonathan L Torres, John E Warner, Kathrin H Kirsch, Stephanie R Weldon, Bettina Groschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R Burton, Daniel Lingwood, Aaron G Schmidt, Usha Nair, Andrew B Ward, William R Schief, Facundo D Batista
Journal: Immunity
PubMed ID: 35987201
Doi: 10.1016/j.immuni.2022.07.020
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Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
Authors: Zhipeng Ai, Xinyu Xiang, Yangquan Xiang, Iwona Szczerbinska, Yuli Qian, Xiao Xu, Chenyang Ma, Yaqi Su, Bing Gao, Hao Shen, Muhammad Nadzim Bin Ramli, Di Chen, Yue Liu, Jia-Jie Hao, Huck Hui Ng, Dan Zhang, Yun-Shen Chan, Wanlu Liu, Hongqing Liang
Journal: Cell Rep
PubMed ID: 36001968
Doi: 10.1016/j.celrep.2022.111240
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