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Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells

Authors: Daniel A Michelson, Koji Hase, Tsuneyasu Kaisho, Christophe Benoist, Diane Mathis

Journal: Cell

PubMed ID: 35714609

Doi: 10.1016/j.cell.2022.05.018

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Immunoinformatics Aided Design and Validation of a Cross-Reactive Peptide Based Multi-Epitope Vaccine Targeting Multiple Serotypes of Dengue Virus

Authors: Vikas Kaushik, Sunil Krishnan G, Lovi Raj Gupta, Utkarsh Kalra, Abdul Rajjak Shaikh, Luigi Cavallo, Mohit Chawla

Journal: Front Immunol

PubMed ID: 35799781

Doi: 10.3389/fimmu.2022.865180

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TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules

Authors: Andrew C McShan, Christine A Devlin, Georgia F Papadaki, Yi Sun, Adam I Green, Giora I Morozov, George M Burslem, Erik Procko, Nikolaos G Sgourakis

Journal: Nat Chem Biol

PubMed ID: 35725941

Doi: 10.1038/s41589-022-01049-9

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Immunogenicity of candidate SARS-CoV-2 DNA vaccines based on the spike protein

Authors: Heeji Lim, Se Eun Kim, Yun Ha Lee, Yun-Ho Hwang, Su Hwan Kim, Mi Young Kim, Gyung Tae Chung, You-Jin Kim, Dokeun Kim, Jung-Ah Lee

Journal: Virology

PubMed ID: 35751974

Doi: 10.1016/j.virol.2022.06.006

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Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization

Authors: Ewa Niedzialkowska, Limin Liu, Cem Kuscu, Zachary Mayo, Wladek Minor, Brian D Strahl, Mazhar Adli, P Todd Stukenberg

Journal: Mol Biol Cell

PubMed ID: 35653296

Doi: 10.1091/mbc.E21-06-0283

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Selenium in Proteins: Conformational Changes Induced by Se Substitution on Methionine, as Studied in Isolated Model Peptides by Optical Spectroscopy and Quantum Chemistry

Authors: Gildas Goldsztejn, Venkateswara Rao Mundlapati, Valérie Brenner, Eric Gloaguen, Michel Mons

Journal: Molecules

PubMed ID: 35630640

Doi: 10.3390/molecules27103163

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New insights into the mechanism of iron transport through the bacterial Ftr system present in pathogens

Authors: Anne Soisig Steunou, Armelle Vigouroux, Magali Aumont-Nicaise, Stéphane Plancqueel, Alain Boussac, Soufian Ouchane, Solange Moréra

Journal: FEBS J

PubMed ID: 35527501

Doi: 10.1111/febs.16476

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Structure and Mechanism of a Cold-Adapted Bacterial Lipase

Authors: Florian van der Ent, Bjarte A Lund, Linn Svalberg, Miha Purg, Ghislean Chukwu, Mikael Widersten, Geir V Isaksen, Bjørn O Brandsdal, Johan Åqvist

Journal: Biochemistry

PubMed ID: 35503728

Doi: 10.1021/acs.biochem.2c00087

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Carboxymethylcellulose biofunctionalized ternary quantum dots for subcellular-targeted brain cancer nanotheranostics

Authors: Alexandra A P Mansur, Mayara R B Paiva, Oliver A L Cotta, Luciana M Silva, Isadora C Carvalho, Nádia S V Capanema, Sandhra M Carvalho, Érica A Costa, Nelson R Martin, Roselene Ecco, Beatriz S Santos, Silvia L Fialho, Zélia I P Lobato, Herman S Mansur

Journal: Int J Biol Macromol

PubMed ID: 35513094

Doi: 10.1016/j.ijbiomac.2022.04.207

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Electrostatics Drive the Molecular Chaperone BiP to Preferentially Bind Oligomerized States of a Client Protein

Authors: Erin E Deans, Judy L M Kotler, Wei-Shao Wei, Timothy O Street

Journal: J Mol Biol

PubMed ID: 35597552

Doi: 10.1016/j.jmb.2022.167638

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