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A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy

Authors: Maryamsadat Seyedsadr, Madison Bang, Ethan McCarthy, Shirley Zhang, Ho-Chung Chen, Mahnia Mohebbi, Willy Hugo, Jason K Whitmire, Melissa G Lechner, Maureen A Su

Journal: biorxiv

PubMed ID: 38260637

Doi: 10.1101/2024.01.07.574553

Products & Services: ORF cDNA Clones/MolecularCloud

Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Authors: Yi-Wen Wu, Wei-Chun HuangFu, Tony Eight Lin, Chao-Hsiang Peng, Huang-Ju Tu, Ting-Yi Sung, Tzu-Ying Sung, Shih-Chung Yen, Shiow-Lin Pan, Kai-Cheng Hsu

Journal: Int J Biol Macromol

PubMed ID: 38163507

Doi: 10.1016/j.ijbiomac.2023.129074

Products & Services: ORF cDNA Clones/MolecularCloud

Structure and design of Langya virus glycoprotein antigens

Authors: Zhaoqian Wang, Matthew McCallum, Lianying Yan, William Sharkey, Young-Jun Park, Ha V Dang, Moushimi Amaya, Ashley Person, Christopher C Broder, David Veesler

Journal: biorxiv

PubMed ID: 37645760

Doi: 10.1101/2023.08.20.554025

Products & Services: ORF cDNA Clones/MolecularCloud

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe

Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim

Journal: Nucleic Acids Research

PubMed ID: 37144518

Doi: 10.1093/nar/gkad363

Products & Services: ORF cDNA Clones/MolecularCloud

S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction

Authors: Liam Butler , Carolina Locatelli , Despoina Allagioti , Irina Lousa , Kimon Lemonidis , Nicholas C O Tomkinson , Christine Salaun , Luke H Chamberlain

Journal: J Biol Chem

PubMed ID: 36442513

Doi: 10.1016/j.jbc.2022.102754

Products & Services: Mutagenesis Services ORF cDNA Clones/MolecularCloud

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies

Authors: Nadeem Murtaza, Annie A Cheng, Chad O Brown, Durga Praveen Meka, Shuai Hong, Jarryll A Uy, Joelle El-Hajjar, Neta Pipko, Brianna K Unda, Birgit Schwanke, Sansi Xing, Bhooma Thiruvahindrapuram, Worrawat Engchuan, Brett Trost, Eric Deneault, Froylan Calderon de Anda, Bradley W Doble, James Ellis, Evdokia Anagnostou, Gary D Bader, Stephen W Scherer, Yu Lu, Karun K Singh

Journal: Cell Rep

PubMed ID: 36417873

Doi: 10.1016/j.celrep.2022.111678

Products & Services: ORF cDNA Clones/MolecularCloud

Preclinical evaluation of new C-11 labeled benzo-1,4-dioxane PET radiotracers for brain α2C adrenergic receptors

Authors: Santosh Alluri，Seth M. Eisenberg，Laurel A. Grisanti，Miles Tanner，Nora D. Volkow，Sung Won Kim，Kun-Eek Kil

Journal: European Journal of Medicinal Chemistry

Doi: doi.org/10.1016/j.ejmech.2022.114764

Products & Services: ORF cDNA Clones/MolecularCloud

Simple and practical sialoglycan encoding system reveals vast diversity in nature and identifies a universal sialoglycan-recognizing probe derived from AB5 toxin B subunits

Authors: Aniruddha Sasmal, Naazneen Khan, Zahra Khedri, Benjamin P Kellman, Saurabh Srivastava, Andrea Verhagen, Hai Yu, Anders Bech Bruntse, Sandra Diaz, Nissi Varki, Travis Beddoe, Adrienne W Paton, James C Paton, Xi Chen, Nathan E Lewis, Ajit Varki

Journal: Glycobiology

PubMed ID: 36048714

Doi: 10.1093/glycob/cwac057

Products & Services: ORF cDNA Clones/MolecularCloud

Riboflavin salvage by Borrelia burgdorferi supports carbon metabolism and is essential for survival in the tick vector

Authors: Darlene Ramos, Amanda G Lasseter, Crystal L Richards, Benjamin Schwarz, Susmita Ghosh, Berta Victoria, Catharine M Bosio, Frank C Gherardini, Mollie W Jewett

Journal: Mol Microbiol

PubMed ID: 36054485

Doi: 10.1111/mmi.14977

Products & Services: ORF cDNA Clones/MolecularCloud

A Secreted Form of the Hepatitis E Virus ORF2 Protein: Design Strategy, Antigenicity and Immunogenicity

Authors: Zihao Chen, Shaoqi Guo, Guanghui Li, Dong Ying, Guiping Wen, Mujin Fang, Yingbin Wang, Zimin Tang, Zizheng Zheng, Ningshao Xia

Journal: Viruses

PubMed ID: 36298677

Doi: 10.3390/v14102122

Products & Services: ORF cDNA Clones/MolecularCloud

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