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The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway

Authors: Ling Wang, Mary E A Howell, Ayrianna Sparks-Wallace, Juan Zhao, Culton R Hensley, Camri A Nicksic, Shanna R Horne, Kaylea B Mohr, Jonathan P Moorman, Zhi Q Yao, Shunbin Ning

Journal: MBio

PubMed ID: 34488443

Doi: 10.1128/mBio.01097-21

Products & Services: GenCrispr Cas9 Genome Editing

Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting

Authors: Beatrice Parma, Vignesh Ramesh, Paradesi Naidu Gollavilli, Aarif Siddiqui, Luisa Pinna, Annemarie Schwab, Sabine Marschall, Shuman Zhang, Christian Pilarsky, Francesca Napoli, Marco Volante, Sophia Urbanczyk, Dirk Mielenz, Henrik Daa Schrøder, Marc Stemmler, Heiko Wurdak, Paolo Ceppi

Journal: J Exp Clin Cancer Res

PubMed ID: 34364401

Doi: 10.1186/s13046-021-02049-8

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Industry updates from the field of stem cell research and regenerative medicine in June 2021

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 34387128

Doi: 10.2217/rme-2021-0097

Products & Services: GenCrispr Cas9 Genome Editing

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters

Authors: Gamma Chi, Rebecca Ebenhoch, Henry Man, Haiping Tang, Laurence E Tremblay, Gabriella Reggiano, Xingyu Qiu, Tina Bohstedt, Idlir Liko, Fernando G Almeida, Alexandre P Garneau, Dong Wang, Gavin McKinley, Christophe P Moreau, Kiran D Bountra, Patrizia Abrusci, Shubhashish M M Mukhopadhyay, Alejandra Fernandez-Cid, Samira Slimani, Julie L Lavoie, Nicola A Burgess-Brown, Ben Tehan, Frank DiMaio, Ali Jazayeri, Paul Isenring, Carol V Robinson, Katharina L Dürr

Journal: EMBO J

PubMed ID: 34031912

Doi: 10.15252/embj.2020107294

Products & Services: GenCrispr Cas9 Genome Editing

ReMOT Control Delivery of CRISPR-Cas9 Ribonucleoprotein Complex to Induce Germline Mutagenesis in the Disease Vector Mosquitoes Culex pipiens pallens (Diptera: Culicidae)

Authors: Xixi Li, Yang Xu, Hongbo Zhang, Haitao Yin, Dan Zhou, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu

Journal: J Med Entomol

PubMed ID: 33590868

Doi: 10.1093/jme/tjab016

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Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector

Authors: Brenda J Seymour, Swati Singh, Hannah M Certo, Karen Sommer, Blythe D Sather, Socheath Khim, Courtnee Clough, Malika Hale, Joseph Pangallo, Byoung Y Ryu, Iram F Khan, Jennifer E Adair, David J Rawlings

Journal: Mol Ther Methods Clin Dev

PubMed ID: 33718514

Doi: 10.1016/j.omtm.2021.01.007

Products & Services: GenCrispr Cas9 Genome Editing

Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1.

Authors: Seo Y,Anh NH,Heo Y,Park SH,Kiem PV,Lee Y,Yen DTH,Jo S,Jeon D,Tai BH,Nam NH,Minh CV,Kim SH,Nhiem NX,Namkung W

Journal: International Journal of Molecular Sciences

PubMed ID: 32899792

Doi: 10.3390/ijms21186470

Products & Services: GenCrispr Cas9 Genome Editing

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing.

Authors: Wei T,Cheng Q,Min YL,Olson EN,Siegwart DJ