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Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
Authors: Jiaxin Chen, Yizheng Wu, Xin Luo, Dongai Jin, Wei Zhou, Zhenyu Ju, Di Wang, Qing Meng, Huijuan Wang, Xiaotian Fu, Jianbin Xu, Zhangfa Song
Journal: Theranostics
PubMed ID: 34158864
Doi: 10.7150/thno.59546
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The surface of lipid droplets constitutes a barrier for endoplasmic reticulum-resident integral membrane proteins
Authors: Rasha Khaddaj, Muriel Mari, Stéphanie Cottier, Fulvio Reggiori, Roger Schneiter
Journal: J Cell Sci
PubMed ID: 34028531
Doi: 10.1242/jcs.256206
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A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation
Authors: Sisi Kang, Mei Yang, Suhua He, Yueming Wang, Xiaoxue Chen, Yao-Qing Chen, Zhongsi Hong, Jing Liu, Guanmin Jiang, Qiuyue Chen, Ziliang Zhou, Zhechong Zhou, Zhaoxia Huang, Xi Huang, Huanhuan He, Weihong Zheng, Hua-Xin Liao, Fei Xiao, Hong Shan, Shoudeng Chen
Journal: Nat Commun
PubMed ID: 33976229
Doi: 10.1038/s41467-021-23036-9
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Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage
Authors: Sheena Dass, Serena Shunmugam, Laurence Berry, Christophe-Sebastien Arnold, Nicholas J Katris, Samuel Duley, Fabien Pierrel, Marie-France Cesbron-Delauw, Yoshiki Yamaryo-Botté, Cyrille Y Botté
Journal: Nat Commun
PubMed ID: 34001876
Doi: 10.1038/s41467-021-22956-w
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Dimeric Her2-specific affibody mediated cisplatin-loaded nanoparticles for tumor enhanced chemo-radiotherapy
Authors: Haijun Wang, Dianlong Jia, Dandan Yuan, Xiaolei Yin, Fengjiao Yuan, Feifei Wang, Wenna Shi, Hui Li, Li-Min Zhu, Qing Fan
Journal: J Nanobiotechnology
PubMed ID: 33985511
Doi: 10.1186/s12951-021-00885-6
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Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
Authors: Tyler N Starr, Nadine Czudnochowski, Fabrizia Zatta, Young-Jun Park, Zhuoming Liu, Amin Addetia, Dora Pinto, Martina Beltramello, Patrick Hernandez, Allison J Greaney, Roberta Marzi, William G Glass, Ivy Zhang, Adam S Dingens, John E Bowen, Jason A Wojcechowskyj, Anna De Marco, Laura E Rosen, Jiayi Zhou, Martin Montiel-Ruiz, Hannah Kaiser, Heather Tucker, Michael P Housley, Julia di Iulio, Gloria Lombardo, Maria Agostini, Nicole Sprugasci, Katja Culap, Stefano Jaconi, Marcel Meury, Exequiel Dellota, Elisabetta Cameroni, Tristan I Croll, Jay C Nix, Colin Havenar-Daughton, Amalio Telenti, Florian A Lempp, Matteo S Pizzuto, John D Chodera, Christy M Hebner, Sean P J Whelan, Herbert W Virgin, David Veesler, Davide Corti, Jesse D Bloom, Gyorgy Snell
Journal: biorxiv
PubMed ID: 33851154
Doi: 10.1101/2021.04.06.438709
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The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors
Authors: Lucia Silvestrini, Norhan Belhaj, Lucia Comez, Yuri Gerelli, Antonino Lauria, Valeria Libera, Paolo Mariani, Paola Marzullo, Maria Grazia Ortore, Antonio Palumbo Piccionello, Caterina Petrillo, Lucrezia Savini, Alessandro Paciaroni, Francesco Spinozzi
Journal: Sci Rep
PubMed ID: 33927258
Doi: 10.1038/s41598-021-88630-9
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Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids
Authors: Dongyoon Kim, Yina Wu, Gayong Shim, Yu-Kyoung Oh
Journal: Pharmaceutics
PubMed ID: 33916667
Doi: 10.3390/pharmaceutics13040490
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Diversity of Functionally Distinct Clonal Sets of Human Conventional Memory B Cells That Bind Staphylococcal Protein A
Authors: Emily E Radke, Zhi Li, David N Hernandez, Hanane El Bannoudi, Sergei L Kosakovsky Pond, Bo Shopsin, Peter Lopez, David Fenyö, Gregg J Silverman
Journal: Front Immunol
PubMed ID: 33995388
Doi: 10.3389/fimmu.2021.662782
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The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD
Authors: Allison J Greaney, Andrea N Loes, Lauren E Gentles, Katharine H D Crawford, Tyler N Starr, Keara D Malone, Helen Y Chu, Jesse D Bloom
Journal: biorxiv
PubMed ID: 33880474
Doi: 10.1101/2021.04.14.439844
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