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TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells
Authors: Bruno Silva, Rajika Arora, Silvia Bione, Claus M Azzalin
Journal: Nat Commun
PubMed ID: 34145295
Doi: 10.1038/s41467-021-24097-6
Products & Services: GenParts™ DNA Fragments   
Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates
Authors: So-Hee Hong, Hanseul Oh, Yong Wook Park, Hye Won Kwak, Eun Young Oh, Hyo-Jung Park, Kyung Won Kang, Green Kim, Bon-Sang Koo, Eun-Ha Hwang, Seung Ho Baek, Hyeong-Jun Park, Yu-Sun Lee, Yoo-Jin Bang, Jae-Yong Kim, Seo-Hyeon Bae, Su Jeen Lee, Ki-Weon Seo, Hak Kim, Taewoo Kwon, Ji-Hwan Kim, Seonghwan Lee, Eunsom Kim, Yeonhwa Kim, Jae-Hak Park, Sang-In Park, Marta Gonçalves, Byung Mook Weon, Haengdueng Jeong, Ki Taek Nam, Kyung-Ah Hwang, Jihye Kim, Hun Kim, Sang-Myeong Lee, Jung Joo Hong, Jae-Hwan Nam
Journal: Sci Adv
PubMed ID: 34049881
Doi: 10.1126/sciadv.abg7156
Products & Services: GenParts™ DNA Fragments   
Re-emerging Aspartic Protease Targets: Examining Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
Authors: Robin Kryštůfek, Pavel Šácha, Jana Starková, Jiří Brynda, Martin Hradilek, Eva Tloušt'ová, Justyna Grzymska, Wioletta Rut, Michael J Boucher, Marcin Drąg, Pavel Majer, Miroslav Hájek, Pavlína Řezáčová, Hiten D Madhani, Charles S Craik, Jan Konvalinka
Journal: J Med Chem
PubMed ID: 34006103
Doi: 10.1021/acs.jmedchem.0c02177
Products & Services: GenParts™ DNA Fragments   
Production of Betacyanins in Transgenic Increases Tolerance to Salinity
Authors: Yanfei Zhou, Tanja Karl, David H Lewis, Tony K McGhie, Steve Arathoon, Kevin M Davies, Ken G Ryan, Kevin S Gould, Kathy E Schwinn
Journal: Front Plant Sci
PubMed ID: 33995448
Doi: 10.3389/fpls.2021.653147
Products & Services: GenParts™ DNA Fragments   
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation
Authors: Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W Kim, John M Herndon, Michelle K Becker-Hapak, Beatriz M Carreno, Nancy B Myers, Mark A Sturmoski, Michael D McLellan, Christopher A Miller, Tanner M Johanns, Benjamin R Tan, Gavin P Dunn, Timothy P Fleming, Ted H Hansen, S Peter Goedegebuure, William E Gillanders
Journal: Genome Med
PubMed ID: 33879241
Doi: 10.1186/s13073-021-00872-4
Products & Services: GenParts™ DNA Fragments   
VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
Authors: Cajsa Davegårdh, Johanna Säll, Anna Benrick, Christa Broholm, Petr Volkov, Alexander Perfilyev, Tora Ida Henriksen, Yanling Wu, Line Hjort, Charlotte Brøns, Ola Hansson, Maria Pedersen, Jens U Würthner, Klaus Pfeffer, Emma Nilsson, Allan Vaag, Elisabet Stener-Victorin, Karolina Pircs, Camilla Scheele, Charlotte Ling
Journal: Nat Commun
PubMed ID: 33893273
Doi: 10.1038/s41467-021-22068-5
Products & Services: GenParts™ DNA Fragments   
Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module
Authors: Nicholas A Arce, Wenpeng Cao, Alexander K Brown, Emily R Legan, Moriah S Wilson, Emma-Ruoqi Xu, Michael C Berndt, Jonas Emsley, X Frank Zhang, Renhao Li
Journal: Nat Commun
PubMed ID: 33883551
Doi: 10.1038/s41467-021-22634-x
Products & Services: GenParts™ DNA Fragments   
Phosphorylation Sites in the Hypervariable Domain in Chikungunya Virus nsP3 Are Crucial for Viral Replication
Authors: Mona Teppor, Eva Žusinaite, Andres Merits
Journal: J Virol
PubMed ID: 33568506
Doi: 10.1128/JVI.02276-20
Products & Services: GenParts™ DNA Fragments   Gene Synthesis   
Functional testing for variant prioritization in a family with long QT syndrome
Authors: Maliheh Najari Beidokhti, Alexander C Bertalovitz, Weizhen Ji, Jorge McCormack, Lauren Jeffries, Emily Sempou, Mustafa K Khokha, Thomas V McDonald, Saquib A Lakhani
Journal: Mol Genet Genomics
PubMed ID: 33876311
Doi: 10.1007/s00438-021-01780-3
Products & Services: GenParts™ DNA Fragments   
Vaccine Efficacy of Self-Assembled Multimeric Protein Scaffold Particles Displaying the Glycoprotein Gn Head Domain of Rift Valley Fever Virus
Authors: Paul J Wichgers Schreur, Mirriam Tacken, Benjamin Gutjahr, Markus Keller, Lucien van Keulen, Jet Kant, Sandra van de Water, Yanyin Lin, Martin Eiden, Melanie Rissmann, Felicitas von Arnim, Rebecca König, Alexander Brix, Catherine Charreyre, Jean-Christophe Audonnet, Martin H Groschup, Jeroen Kortekaas
Journal: Vaccines (Basel)
PubMed ID: 33806789
Doi: 10.3390/vaccines9030301
Products & Services: GenParts™ DNA Fragments   

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