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Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

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Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia

Authors: Gianna M Branella, Jasmine Y Lee, Jennifer Okalova, Kiran K Parwani, Jordan S Alexander, Raquel F Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C Brown, Shanmuganathan Chandrakasan, Brian G Petrich, Christopher B Doering, H Trent Spencer

Journal: Front Immunol

PubMed ID: 38022523

Doi: 10.3389/fimmu.2023.1294555

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Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs

Authors: Ghasidit Pornnoppadol, Layne G Bond, Michael J Lucas, Jennifer M Zupancic, Yun-Huai Kuo, Boya Zhang, Colin F Greineder, Peter M Tessier

Journal: Cell Chem Biol

PubMed ID: 37890480

Doi: 10.1016/j.chembiol.2023.09.008

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Whole-genome sequence and mass spectrometry study of the snow blight fungus Phacidium infestans (Karsten) DSM 5139 growing at freezing temperatures

Authors: C Zerouki, K Chakraborty, S Kuittinen, A Pappinen, O Turunen

Journal: Mol Genet Genomics

PubMed ID: 37815644

Doi: 10.1007/s00438-023-02073-7

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Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury

Authors: Liushenyan Yu, Junchao Xue, Yanyan Wu, Hanyu Zhou

Journal: Folia Histochem Cytobiol

PubMed ID: 37787035

Doi: 10.5603/fhc.95291

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Varying the expression pattern of the strigolactone receptor gene results in phenotypes distinct from both wild type and knockout mutants

Authors: Revel S M Drummond, Hui Wen Lee, Zhiwei Luo, Jack F Dakin, Bart J Janssen, Kimberley C Snowden

Journal: Front Plant Sci

PubMed ID: 37900765

Doi: 10.3389/fpls.2023.1277617

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Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

Authors: Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed Salah Mahmoud, Iratxe Ugarte Zabala, Jing Zeng, Scott B Ficarro, Denise Klatt, Christian Brendel, Alessandro Rambaldi, Jerome Ritz , Jarrod A Marto, Danilo Pellin, Daniel E Bauer, Scott A Armstrong, Pietro Genovese

Journal: Nature

PubMed ID: 37648862

Doi: 10.1038/s41586-023-06496-5

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Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake

Authors: Rodger de Miranda, Bonnie J Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Mark Arbing, Paul J Sieminski, Kadamba Papavinasasundaram, Sumer Abdul-Hafiz, Sum Chan, Christopher M Sassetti, Sabine Ehrt, Celia W Goulding

Journal: PLoS Pathog

PubMed ID: 37747938

Doi: 10.1371/journal.ppat.1011650

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Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality

Authors: Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm

Journal: biorxiv

PubMed ID: 37781587

Doi: 10.1101/2023.09.19.558375

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Functional diversity of sodium channel variants in common eastern bumblebee, Bombus impatiens

Authors: Longwei Chen, Yuquan Wang, Kun Zhang, Shaoying Wu

Journal: Arch Insect Biochem Physiol

PubMed ID: 37672296

Doi: 10.1002/arch.22052

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