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Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer

Authors: Zhaowei Zhang, Xuyang Liu, Chuanyue Peng, Rui Du, Xiaoqin Hong, Jia Xu, Jiaming Chen, Xiaomin Li, Yujing Tang, Yuwei Li, Yang Liu, Chen Xu, Dingbin Liu

Journal: ACS Nano

PubMed ID: 40033785

Doi: 10.1021/acsnano.4c16698

Products & Services: Synthetic sgRNA and crRNA Service GenCrispr Cas9 Genome Editing

Mismatch prime editing gRNA increased efficiency and reduced indels

Authors: Jidong Fei , Dongdong Zhao , Caiyi Pang , Ju Li , Siwei Li , Wentao Qiao , Juan Tan , Changhao Bi , Xueli Zhang

Journal: Nat Commun

PubMed ID: 39747083

Doi: 10.1038/s41467-024-55578-z

Products & Services: Synthetic sgRNA and crRNA Service

Remotely Sequential Activation of Biofunctional MXenes for Spatiotemporally Controlled Photothermal Cancer Therapy Integrated with Multimodal Imaging

Authors: Jing Jia , Xiaobo Zhang , Yiran Li , Tian Wang , Ying An , Xinrong Yan , Bin Liu , Chaoyi Yang , Huangxian Ju

Journal: Small

PubMed ID: 39665387

Doi: 10.1002/smll.202410535

Products & Services: Synthetic sgRNA and crRNA Service

Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia

Authors: Rui-Jin Ji , Guo-Hua Cao , Wei-Qiang Zhao , Mu-Yao Wang , Pan Gao, Yi-Zhou Zhang, Xue-Bin Wang, Hou-Yuan Qiu , Di-Di Chen, Xiao-Han Tong , Min Duan, Hao Yin, Ying Zhang

Journal: Cell Stem Cell

PubMed ID: 39353428

Doi: 10.1016/j.stem.2024.09.003

Products & Services: Synthetic sgRNA and crRNA Service

Inhalation of Bioorthogonal Gene-Editable Spiky-Pollen Reprograms Tumor-Associated Macrophages for Lung Cancer Immunotherapy

Authors: Qianglan Lu , Ruiyue Chen , Fei Zeng, Zhiyong Liu, Yongchun Pan, Yanfeng Gao, Bangshun He and Yujun Song

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202408767

Products & Services: Synthetic sgRNA and crRNA Service

Rapid generation of long, chemically modified pegRNAs for prime editing

Authors: Xinlin Lei , Anhui Huang , Didi Chen , Xuebin Wang , Ruijin Ji , Jinlin Wang , Yizhou Zhang , Yuming Zhang , Shuhan Lu , Kun Zhang , Qiubing Chen , Ying Zhang , Hao Yin

Journal: Nature Biotechnology

PubMed ID: 39349835

Doi: doi.org/10.1038/s41587-024-02394-x

Products & Services: Custom DNA/RNA Oligos Gene Synthesis Synthetic sgRNA and crRNA Service

SpRY-mediated screens facilitate functional dissection of non-coding sequences at single-base resolution

Authors: Yao Yao, Zhiwei Zhou, Xiaoling Wang, Zhirui Liu, Yixin Zhai, Xiaolin Chi, Jingyi Du, Liheng Luo, Zhigang Zhao, Xiaoyue Wang, Chaoyou Xue, Shuquan Rao

Journal: Cell Genom

PubMed ID: 38889719

Doi: 10.1016/j.xgen.2024.100583

Products & Services: Synthetic sgRNA and crRNA Service

nCas9 Engineering for Improved Target Interaction Presents an Effective Strategy to Enhance Base Editing

Authors: Guiquan Zhang, Ziguo Song, Shisheng Huang, Yafeng Wang, Jiayuan Sun, Lu Qiao, Guanglei Li, Yuanyuan Feng, Wei Han, Jin Tang, Yulin Chen, Xingxu Huang, Furui Liu, Xiaolong Wang, Jianghuai Liu

Journal: Adv Sci (Weinh)

PubMed ID: 38881503

Doi: 10.1002/advs.202405426

Products & Services: Synthetic sgRNA and crRNA Service

Structure and genome editing of type I-B CRISPR-Cas

Authors: Meiling Lu, Chenlin Yu, Yuwen Zhang, Wenjun Ju, Zhi Ye, Chenyang Hua, Jinze Mao, Chunyi Hu, Zhenhuang Yang & Yibei Xiao

Journal: Nat Commun

PubMed ID: 38750051

Doi: 10.1038/s41467-024-48598-2

Products & Services: Synthetic sgRNA and crRNA Service Plasmid DNA Preparation

Tracking single-cell evolution using clock-like chromatin accessibility loci

Authors: Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang & Yi Zhang