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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
Authors: Anna Worthmann , Julius Ridder , Sharlaine Y L Piel , Ioannis Evangelakos , Melina Musfeldt , Hannah Voß , Marie O'Farrell , Alexander W Fischer , Sangeeta Adak , Monica Sundd , Hasibullah Siffeti , Friederike Haumann , Katja Kloth , Tatjana Bierhals , Markus Heine , Paul Pertzborn , Mira Pauly , Julia-Josefine Scholz , Suman Kundu , Marceline M Fuh , Axel Neu , Klaus Tödter , Maja Hempel , Uwe Knippschild , Clay F Semenkovich , Hartmut Schlüter , Joerg Heeren , Ludger Scheja , Christian Kubisch , Christian Schlein
Journal: Nat Commun
PubMed ID: 38167725
Doi: 10.1038/s41467-023-44364-y
Products & Services: Custom Vector Construction   
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding
Authors: Paolo Pizzul, Erika Casari, Carlo Rinaldi, Marco Gnugnoli, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese
Journal: Nucleic Acids Res
PubMed ID: 38180815
Doi: 10.1093/nar/gkad1246
Products & Services: Gene Synthesis   
A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease
Authors: Su-Jeong Kim, Brendan Miller, Nicolas G Hartel, Ricardo Ramirez, Regina Gonzalez Braniff, Naphada Leelaprachakul, Amy Huang, Yuzhu Wang, Thalida Em Arpawong, Eileen M Crimmins, Penglong Wang, Xianbang Sun, Chunyu Liu, Daniel Levy, Kelvin Yen, Giselle M Petzinger, Nicholas A Graham, Michael W Jakowec, Pinchas Cohen
Journal: Mol Psychiatry
PubMed ID: 38167865
Doi: 10.1038/s41380-023-02344-0
Products & Services: Peptide Synthesis   
Leafhopper salivary vitellogenin mediates virus transmission to plant phloem
Authors: Yanfei Wang , Chengcong Lu , Shude Guo , Yuxin Guo , Taiyun Wei , Qian Chen
Journal: Nat Commun
PubMed ID: 38167823
Doi: 10.1038/s41467-023-43488-5
Products & Services: Polyclonal Antibody Services   
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
Authors: Christopher M. Hickey, Katherine M. Digianantonio, Kurt Zimmermann  , Alicia Harbin, Connor Quinn, Avani Patel, Peter Gareiss  , Amanda Chapman1 , Bernadette Tiberi1,2, Jennifer Dobrodziej1,3, John Corradi1 , Angela M. Cacace1 , David R. Langley & Miklós Békés
Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY
Doi: 10.1038/s41594-023-01146-w
Products & Services: Peptide Synthesis   Gene Synthesis   
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Authors: Nagaraja Chappidi 1, Thomas Quail 2, Simon Doll 3, Laura T Vogel 4, Radoslav Aleksandrov 5, Suren Felekyan 4, Ralf Kühnemuth 4, Stoyno Stoynov 5, Claus A M Seidel 4, Jan Brugués 6, Marcus Jahnel 3, Titus M Franzmann 1, Simon Alberti
Journal: Cell
PubMed ID: 38320550
Doi: 10.1016/j.cell.2024.01.015
Products & Services: Codon Optimization   
The CRISPR effector Cam1 mediates membrane depolarization for phage defence
Authors: Christian F. Baca, You Yu, Jakob T. Rostøl, Puja Majumder, Dinshaw J. Patel & Luciano A. Marraffini
Journal: Nature
PubMed ID: 38200316
Doi: 10.1038/s41586-023-06902-y
Products & Services: GenCrispr Cas9 Genome Editing   
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria
Authors: Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling
Journal: Cell
PubMed ID: 38199007
Doi: 10.1016/j.molcel.2023.12.013
Products & Services: Gene Synthesis   
Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis
Authors: Zhong-Hao Ji, Wen-Yin Xie , Pei-Sen Zhao , Hong-Yu Wu , Wen-Zhi Ren , Jin-Ping Hu , Wei Gao , Bao Yuan
Journal: Nutrients .
PubMed ID: 38140314
Doi: 10.3390/nu15245055
Products & Services: Peptide Synthesis   
Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
Authors: Leonardo A Parra-Rivas , Kayalvizhi Madhivanan , Brent D Aulston , Lina Wang , Dube Dheeraj Prakashchand , Nicholas P Boyer , Veronica M Saia-Cereda , Kristen Branes-Guerrero , Donald P Pizzo , Pritha Bagchi , V S Sundar , Yong Tang , Utpal Das , David A Scott , Padmini Rangamani , Yuki Ogawa , Subhojit Roy
Journal: Neuron .
PubMed ID: 38128479
Doi: 10.1016/j.neuron.2023.11.020
Products & Services: Gene Services   

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