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页码: 103/1026 每页显示数量

FOXM1 regulates glycolysis and energy production in multiple myeloma

Authors: Yan Cheng, Fumou Sun, Krista Thornton, Xuefang Jing, Jing Dong, Grant Yun, Michael Pisano, Fenghuang Zhan, Sung Hoon Kim, John A Katzenellenbogen, Benita S Katzenellenbogen, Parameswaran Hari, Siegfried Janz

Journal: Oncogene

PubMed ID: 35794249

Doi: 10.1038/s41388-022-02398-4

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Expression of phenylalanine ammonia lyase as an intracellularly free and extracellularly cell surface-immobilized enzyme on a gut microbe as a live biotherapeutic for phenylketonuria

Authors: Yu Jiang, Bingbing Sun, Fenghui Qian, Feng Dong, Chongmao Xu, Wuling Zhong, Rui Huang, Qiwei Zhai, Yu Jiang, Sheng Yang

Journal: Sci China Life Sci

PubMed ID: 35907113

Doi: 10.1007/s11427-021-2137-3

Products & Services: Gene Synthesis

Microfluidic Paper-Based Preconcentration and Retrieval for Rapid Ribonucleic Acid Biomarker Detection and Visualization

Authors: Yannan Yu, Fengya Fan, Zachary J Smith, Xi Wei

Journal: Anal Chem

PubMed ID: 35858837

Doi: 10.1021/acs.analchem.2c01442

Products & Services: Molecular Biology Tools

Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model

Authors: Kyle Rosenke, Atsushi Okumura, Matthew C Lewis, Friederike Feldmann, Kimberly Meade-White, W Forrest Bohler, Amanda Griffin, Rebecca Rosenke, Carl Shaia, Michael A Jarvis, Heinz Feldmann

Journal: JCI Insight

PubMed ID: 35579953

Doi: 10.1172/jci.insight.160108

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HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS

Authors: Elke Braems, Valérie Bercier, Evelien Van Schoor, Kara Heeren, Jimmy Beckers, Laura Fumagalli, Lieselot Dedeene, Matthieu Moisse, Ilse Geudens, Nicole Hersmus, Arpan R Mehta, Bhuvaneish T Selvaraj, Siddharthan Chandran, Ritchie Ho, Dietmar R Thal, Philip Van Damme, Bart Swinnen, Ludo Van Den Bosch

Journal: Acta Neuropathol

PubMed ID: 35895140

Doi: 10.1007/s00401-022-02471-y

Products & Services: Proteins, Expression, Isolation and Analysis

KIL1 terminates fertility in maize by controlling silk senescence

Authors: M Ria Šim Škov, Anna Daneva, Nicolas Doll, Neeltje Schilling, Marta Cubr A-Rad O, Liangzi Zhou, Freya De Winter, Stijn Aesaert, Riet De Rycke, Laurens Pauwels, Thomas Dresselhaus, Norbert Brugi Re, Carl R Simmons, Jeffrey E Habben, Moritz K Nowack

Journal: Plant Cell

PubMed ID: 35608197

Doi: 10.1093/plcell/koac151

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The structure of Vibrio cholerae FeoC reveals conservation of the helix-turn-helix motif but not the cluster-binding domain

Authors: Janae B Brown, Mark A Lee, Aaron T Smith

Journal: J Biol Inorg Chem

PubMed ID: 35796835

Doi: 10.1007/s00775-022-01945-4

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

Authors: Ryan J Boyd, Tien L Olson, James D Zook, Derek Stein, Manuel Aceves, Wan-Hsin Lin, Felicia M Craciunescu, Debra T Hansen, Panos Z Anastasiadis, Abhishek Singharoy, Petra Fromme

Journal: FASEB J

PubMed ID: 35639414

Doi: 10.1096/fj.202101808RR

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Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV

Authors: Meisam Naeimi Kararoudi, Shibi Likhite, Ezgi Elmas, ..., Branden S. Moriarity, Kathrin Meyer, Dean A. Lee

Journal: CellPress

Doi: crmeth.2022.100236

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Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway.

Authors: Shenglong Zhu, Jingwei Zhang, Xuan Jiang, Wei Wang, Yong Q Chen

Journal: EBioMedicine

PubMed ID: 35588628

Doi: 10.1016/j.ebiom.2022.104060

Products & Services: PCR Cloning and Subcloning

Agrochemical control of gene expression using evolved split RNA polymerase

Authors: Yuan Yuan , Jin Miao

Journal: PeerJ

PubMed ID: 35729907

Doi: doi.org/10.7717/peerj.13619

Products & Services: Gene Synthesis

Nociceptor Neurons are Involved in the Host Response to Urinary Tract Infections

Authors: Zhengdong Gao, Yaxiao Liu, Lekai Zhang, Zizhuo Yang, Linchen Lv, Shuai Wang, Lipeng Chen, Nan Zhou, Yaofeng Zhu, Xuewen Jiang, Benkang Shi, Yan Li

Journal: J Inflamm Res

PubMed ID: 35702548

Doi: 10.2147/JIR.S356960

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Humoral and Cellular Responses to BNT162b2 as a Booster Following Two Doses of ChAdOx1 nCov-19 Determined Using Three SARS-CoV-2 Antibody Assays and an Interferon-Gamma Release Assay: A Prospective Longitudinal Study in Healthcare Workers

Authors: Seri Jeong, Nuri Lee, Su Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Hyun Soo Kim

Journal: Front Immunol

PubMed ID: 35720318

Doi: 10.3389/fimmu.2022.859019

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Using field evaluation and systematic iteration to rationalize the accumulation of omega-3 long-chain polyunsaturated fatty acids in transgenic Camelina sativa

Authors: Lihua Han, Susana Silvestre, Olga Sayanova, Richard P Haslam, Johnathan A Napier

Journal: Plant Biotechnol J

PubMed ID: 35656640

Doi: 10.1111/pbi.13867

Products & Services: Codon Optimization

Visualizing molecules of functional profilin

Authors: Morgan L Pimm, Xinbei Liu, Farzana Tuli, Jennifer Heritz, Ashley Lojko, Jessica L Henty-Ridilla

Journal: Elife

PubMed ID: 35666129

Doi: 10.7554/eLife.76485

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Synergistic interaction of Cry1Ah and Vip3Aa19 proteins combination with midgut ATP-binding cassette subfamily C receptors of Conogethes punctiferalis (Guenée) (Lepidoptera: Crambidae)

Authors: Su Mon Shwe, Sivaprasath Prabu, Dapeng Jing, Kanglai He, Zhenying Wang

Journal: Int J Biol Macromol

PubMed ID: 35690160

Doi: 10.1016/j.ijbiomac.2022.06.019

Products & Services: Proteins, Expression, Isolation and Analysis

Circular ribonucleic acid nucleoporin 98 knockdown alleviates high glucose-induced proliferation, fibrosis, inflammation and oxidative stress in human glomerular mesangial cells by regulating the microribonucleic acid-151-3p-high mobility group AT-hook 2 axis

Authors: Qianlan Dong, Longhao Dong, Yanting Zhu, Xiaoming Wang, Zhenjiang Li, Linping Zhang

Journal: J Diabetes Investig

PubMed ID: 35482475

Doi: 10.1111/jdi.13821

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Tomato brown rugose fruit virus resistance generated by quadruple knockout of homologs of TOBAMOVIRUS MULTIPLICATION1 in tomato

Authors: Masayuki Ishikawa, Tetsuya Yoshida, Momoko Matsuyama, Yusuke Kouzai, Akihito Kano, Kazuhiro Ishibashi

Journal: Plant Physiol

PubMed ID: 35262730

Doi: 10.1093/plphys/kiac103

Products & Services: PCR Cloning and Subcloning

Long-range enhancement of N501Y-endowed mouse infectivity of SARS-CoV-2 by the non-RBD mutations of Ins215KLRS and H655Y

Authors: Yichao Zhu, Wenzhao Zhou, Zubiao Niu, Jiayi Sun, Zhengrong Zhang, Qinqin Li, You Zheng, Chenxi Wang, Lihua Gao, Qiang Sun

Journal: Biol Direct

PubMed ID: 35658928

Doi: 10.1186/s13062-022-00325-x

Products & Services: Mutant Libraries

Identification of Reference Genes for Reverse Transcription-Quantitative PCR Analysis of Ginger Under Abiotic Stress and for Postharvest Biology Studies

Authors: Gang Li, Jiawei Ma, Junliang Yin, Fengling Guo, Keyong Xi, Peihua Yang, Xiaodong Cai, Qie Jia, Lu Li, Yiqing Liu, Yongxing Zhu

Journal: Front Plant Sci

PubMed ID: 35734245

Doi: 10.3389/fpls.2022.893495

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A circular mRNA vaccine prototype producing VFLIP-X spike confers a broad neutralization of SARS-CoV-2 variants by mouse sera

Authors: Chotiwat Seephetdee, Kanit Bhukhai, Nattawut Buasri, Puttipatch Leelukkanaveera, Pat Lerdwattanasombat, Suwimon Manopwisedjaroen, Nut Phueakphud, Sakonwan Kuhaudomlarp, Eduardo Olmedillas, Erica Ollmann Saphire, Arunee Thitithanyanont, Suradej Hongeng, Patompon Wongtrakoongate

Journal: Antiviral Res

PubMed ID: 35772601

Doi: 10.1016/j.antiviral.2022.105370

Products & Services: Codon Optimization

Peptidoglycan maturation controls outer membrane protein assembly

Authors: Gideon Mamou, Federico Corona, Ruth Cohen-Khait, Nicholas G Housden, Vivian Yeung, Dawei Sun, Pooja Sridhar, Manuel Pazos, Timothy J Knowles, Colin Kleanthous, Waldemar Vollmer

Journal: Nature

PubMed ID: 35705811

Doi: 10.1038/s41586-022-04834-7

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Overproduction, Purification, and Stability of the Functionally Active Human Carnitine Acetyl Transferase

Authors: Deborah Giudice, Lara Console, Arduino Arduini, Cesare Indiveri

Journal: Mol Biotechnol

PubMed ID: 35727434

Doi: 10.1007/s12033-022-00522-z

Products & Services: PCR Cloning and Subcloning

Genomic insights into the recent chromosome reduction of autopolyploid sugarcane Saccharum spontaneum

Authors: Qing Zhang, Yiying Qi, Haoran Pan, Haibao Tang, Gang Wang, Xiuting Hua, Yongjun Wang, Lianyu Lin, Zhen Li, Yihan Li, Fan Yu, Zehuai Yu, Yongji Huang, Tianyou Wang, Panpan Ma, Meijie Dou, Zongyi Sun, Yibin Wang, Hengbo Wang, Xingtan Zhang, Wei Yao, Yuntong Wang, Xinlong Liu, Maojun Wang, Jianping Wang, Zuhu Deng, Jingsheng Xu, Qinghui Yang, ZhongJian Liu, Baoshan Chen, Muqing Zhang, Ray Ming, Jisen Zhang

Journal: Nat Genet

PubMed ID: 35654976

Doi: 10.1038/s41588-022-01084-1

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Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma

Authors: Victor O Oria, Hongyi Zhang, Christopher R Zito, Chetan K Rane, Xian-Yong Ma, Olivia K Provance, Thuy T Tran, Adebowale Adeniran, Yuval Kluger, Mario Sznol, Marcus W Bosenberg, Harriet M Kluger, Lucia B Jilaveanu

Journal: Cell Mol Life Sci

PubMed ID: 35737114

Doi: 10.1007/s00018-022-04364-5

Products & Services: Gene Synthesis

SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues

Authors: Siqian Feng, Richard S Mann

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35696584

Doi: 10.1073/pnas.2122900119

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Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186

Authors: Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Ying Zhu, Maia Vinogradova, Robert B DuBridge, Chad May

Journal: J Immunother Cancer

PubMed ID: 35728872

Doi: 10.1136/jitc-2021-004336

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular insights into intra-complex signal transmission during stressosome activation

Authors: Algirdas Miksys, Lifei Fu, M Gregor Madej, Duarte N Guerreiro, Susann Kaltwasser, Maria Conway, Sema Ejder, Astrid Bruckmann, Jon Marles-Wright, Richard J Lewis, Conor O'Byrne, Jan Pané-Farré, Christine Ziegler

Journal: Commun Biol

PubMed ID: 35760945

Doi: 10.1038/s42003-022-03549-9

Products & Services: Proteins, Expression, Isolation and Analysis

GLYCINE-RICH RNA-BINDING PROTEIN 7 potentiates effector-triggered immunity through an RNA recognition motif

Authors: Octavina C A Sukarta, Qi Zheng, Erik J Slootweg, Mark Mekken, Melanie Mendel, Vera Putker, André Bertran, Anouk Brand, Hein Overmars, Rikus Pomp, Jan Roosien, Sjef Boeren, Geert Smant, Aska Goverse

Journal: Plant Physiol

PubMed ID: 35218353

Doi: 10.1093/plphys/kiac081

Products & Services: Gene Synthesis

Heterologous Expression and Characterization of Plant Wax Ester Producing Enzymes

Authors: Daolin Cheng, Ling Li, Ludmila Rizhsky, Priyanka Bhandary, Basil J Nikolau

Journal: Metabolites

PubMed ID: 35888701

Doi: 10.3390/metabo12070577

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Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB-R signaling

Authors: Lihua Chang, Aibin Kong, Yun Guo, Jing Zhang, Yue Sun, Penglu Chen, Xiaofei Wang

Journal: Drug Dev Res

PubMed ID: 35749642

Doi: 10.1002/ddr.21964

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Potential of Aspergillus oryzae as a biosynthetic platform for indigoidine, a non-ribosomal peptide pigment with antioxidant activity

Authors: Sarocha Panchanawaporn, Chanikul Chutrakul, Sukanya Jeennor, Jutamas Anantayanon, Nakul Rattanaphan, Kobkul Laoteng

Journal: PLoS ONE

PubMed ID: 35737654

Doi: 10.1371/journal.pone.0270359

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Microstructured Hydrogels to Guide Self-Assembly and Function of Lung Alveolospheres

Authors: Claudia Loebel, Aaron I Weiner, Madeline K Eiken, Jeremy B Katzen, Michael P Morley, Vikram Bala, Fabian L Cardenas-Diaz, Matthew D Davidson, Kazushige Shiraishi, Maria C Basil, Laura T Ferguson, Jason R Spence, Matthias Ochs, Michael F Beers, Edward E Morrisey, Andrew E Vaughan, Jason A Burdick

Journal: Adv Mater

PubMed ID: 35522531

Doi: 10.1002/adma.202202992

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Lineage-specific insertions in T-box riboswitches modulate antibiotic binding and action

Authors: Nikoleta Giarimoglou, Adamantia Kouvela, Ioanna Patsi, Jinwei Zhang, Vassiliki Stamatopoulou, Constantinos Stathopoulos

Journal: Nucleic Acids Res

PubMed ID: 35580054

Doi: 10.1093/nar/gkac359

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Catalytic Properties of Caseinolytic Protease Subunit of and Its Inhibition by a Member of δ-Lactone, Hyptolide

Authors: Cahyo Budiman, Raimalynah Abd Razak, Angelesa Runin Anak Unggit, Rafida Razali, Meiny Suzery, Ruzaidi Azli Mohd Mokhtar, Ping-Chin Lee, Didik Huswo Utomo

Journal: Molecules

PubMed ID: 35744912

Doi: 10.3390/molecules27123787

Products & Services: Proteins, Expression, Isolation and Analysis

The Specificity of ParR Binding Determines the Incompatibility of Conjugative Plasmids in Clostridium perfringens

Authors: Thomas D Watts, Daouda A K Traore, Sarah C Atkinson, Carmen Lao, Natalie Caltabiano, Julian I Rood, Vicki Adams

Journal: MBio

PubMed ID: 35726914

Doi: 10.1128/mbio.01356-22

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Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology

Authors: Giavanna Paterno, Brach M Bell, Kimberly-Marie M Gorion, Stefan Prokop, Benoit I Giasson

Journal: Acta Neuropathol Commun

PubMed ID: 35765058

Doi: 10.1186/s40478-022-01394-9

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A Novel Synthetic Antibody Library with Complementarity-Determining Region Diversities Designed for an Improved Amplification Profile

Authors: Xuelian Bai, Moonseon Jang, Nam Ju Lee, Thi Thu Ha Nguyen, Mooyoung Jung, Jeong Yeon Hwang, Hyunbo Shim

Journal: Int J Mol Sci

PubMed ID: 35682935

Doi: 10.3390/ijms23116255

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Isogenic GAA-KO Murine Muscle Cell Lines Mimicking Severe Pompe Mutations as Preclinical Models for the Screening of Potential Gene Therapy Strategies

Authors: Araceli Aguilar-González, Juan Elías González-Correa, Eliana Barriocanal-Casado, Iris Ramos-Hernández, Miguel A Lerma-Juárez, Sara Greco, Juan José Rodríguez-Sevilla, Francisco Javier Molina-Estévez, Valle Montalvo-Romeral, Giuseppe Ronzitti, Rosario María Sánchez-Martín, Francisco Martín, Pilar Muñoz

Journal: Int J Mol Sci

PubMed ID: 35682977

Doi: 10.3390/ijms23116298

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Characterization of novel antimicrobial peptides designed on the basis of amino acid sequence of peptides from egg white hydrolysate

Authors: Cunkuan Shen, Yunzhi Lin, Tahir Noor Mohammadi, Yoshimitsu Masuda, Ken-Ichi Honjoh, Takahisa Miyamoto

Journal: Int J Food Microbiol

PubMed ID: 35752018

Doi: 10.1016/j.ijfoodmicro.2022.109802

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Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in

Authors: Xuejin Zhao, Weijia Wei, Yeqing Zong, Chaoxian Bai, Xian Guo, Hua Zhu, Chunbo Lou

Journal: Synth Syst Biotechnol

PubMed ID: 35756964

Doi: 10.1016/j.synbio.2022.05.010

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Pre-existing adaptive immunity to the RNA-editing enzyme Cas13d in humans

Authors: Xin-Zi Emily Tang, Shu Xuan Tan, Shawn Hoon, Gene W Yeo

Journal: Nat Med

PubMed ID: 35668177

Doi: 10.1038/s41591-022-01848-6

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Identification of Antigenic Properties of Acinetobacter baumannii Proteins as Novel Putative Vaccine Candidates Using Reverse Vaccinology Approach

Authors: Tohid Piri-Gharaghie, Abbas Doosti, Seyed Abbas Mirzaei

Journal: Appl Biochem Biotechnol

PubMed ID: 35670904

Doi: 10.1007/s12010-022-03995-5

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COVID-19 redux: clinical, virologic, and immunologic evaluation of clinical rebound after nirmatrelvir/ritonavir

Authors: Brian P Epling, Joseph M Rocco, Kristin L Boswell, Elizabeth Laidlaw, Frances Galindo, Anela Kellogg, Sanchita Das, Allison Roder, Elodie Ghedin, Allie Kreitman, Robin L Dewar, Sophie E M Kelly, Heather Kalish, Tauseef Rehman, Jeroen Highbarger, Adam Rupert, Gregory Kocher, Michael R Holbrook, Andrea Lisco, Maura Manion, Richard A Koup, Irini Sereti

Journal: medrxiv

PubMed ID: 35734093

Doi: 10.1101/2022.06.16.22276392

Divergent cis-regulatory evolution underlies the convergent loss of sodium channel expression in electric fish

Authors: Sarah LaPotin, Mary E Swartz, David M Luecke, Savvas J Constantinou, Jason R Gallant, Johann K Eberhart, Harold H Zakon

Journal: Sci Adv

PubMed ID: 35648851

Doi: 10.1126/sciadv.abm2970

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Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling

Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul

Journal: Biochem J

PubMed ID: 35670457

Doi: 10.1042/BCJ20220037

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Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR)

Authors: Johannes C van der Mijn, Qiuying Chen, Kristian B Laursen, Francesca Khani, Xiaofei Wang, Princesca Dorsaint, Andrea Sboner, Steven S Gross, David M Nanus, Lorraine J Gudas

Journal: Mol Carcinog

PubMed ID: 35726553

Doi: 10.1002/mc.23437

Products & Services: Proteins, Expression, Isolation and Analysis

Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy

Authors: Wen Liu, Yi Zou, Kaiming Li, Haiqing Zhong, Longbo Yu, Shushan Ge, Yisheng Lai, Xianchi Dong, Qiang Xu, Wenjie Guo

Journal: J Immunol

PubMed ID: 35725271

Doi: 10.4049/jimmunol.2100938

Products & Services: Mammalian Expression

Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

Authors: Amy R Rappaport, Sue-Jean Hong, Ciaran D Scallan, Leonid Gitlin, Arvin Akoopie, Gregory R Boucher, Milana Egorova, J Aaron Espinosa, Mario Fidanza, Melissa A Kachura, Annie Shen, Gloria Sivko, Anne Van Abbema, Robert L Veres, Karin Jooss

Journal: Nat Commun

PubMed ID: 35672369

Doi: 10.1038/s41467-022-31005-z

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Linear DNA amplicons as a novel cancer vaccine strategy

Authors: Antonella Conforti, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Clay Shorrock, James A Hayward, Yuhua Sun, Ben Minghwa Liang, Fabio Palombo, Brian Viscount, Luigi Aurisicchio

Journal: J Exp Clin Cancer Res

PubMed ID: 35668533

Doi: 10.1186/s13046-022-02402-5

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