客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 116/1026 每页显示数量

Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells

Authors: Kareem A Heslop, Pieter Burger, Christiana Kappler, Ashish K Solanki, Monika Gooz, Yuri K Peterson, Catherine Mills, Thomas Benton, Stephen A Duncan, Patrick M Woster, Eduardo N Maldonado

Journal: Biomed Pharmacother

PubMed ID: 35447542

Doi: 10.1016/j.biopha.2022.112928

Products & Services: Plasmid DNA Preparation

The development of a candidate of desensitization vaccines against Der f 2 nearly without IgE-binding activity

Authors: Xiao-Jing Ling, Chen Pan, Ling-Xiao Tan, Ying Zhu, Yu-Xing Yang, Xiao-Fei Zeng, Jin-Lyu Sun, Ji-Fu Wei, Chen Lu

Journal: Immunobiology

PubMed ID: 35580444

Doi: 10.1016/j.imbio.2022.152217

Products & Services: Proteins, Expression, Isolation and Analysis

The Model for Mucolipidosis Type IV

Authors: Claire Y Allan, Paul R Fisher

Journal: Front Cell Dev Biol

PubMed ID: 35493081

Doi: 10.3389/fcell.2022.741967

Products & Services: Proteins, Expression, Isolation and Analysis

A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells

Authors: Yumei Li, Lingjun Wu, Yueying Liu, Siwen Ma, Biyi Huang, Xianjing Feng, Hui Wang

Journal: Transl Oncol

PubMed ID: 35477065

Doi: 10.1016/j.tranon.2022.101424

Products & Services: Mammalian Expression

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action

Authors: Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A Zubarev, Stig Linder, Pádraig D'Arcy

Journal: Front Oncol

PubMed ID: 35530310

Doi: 10.3389/fonc.2022.852980

Products & Services: Oligo pool

Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-κB activation through upregulating sirtuin 7 in dental pulp fibroblasts

Authors: Xiaochen Liu, Chunmeng Wang, Liping Pang, Liangliang Pan, Qi Zhang

Journal: Cell Prolif

PubMed ID: 35411569

Doi: 10.1111/cpr.13227

Products & Services: Recombinant Proteins

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Authors: Sachin Wani, Anna Daroszewska, Donald M Salter, Rob J van 't Hof, Stuart H Ralston, Omar M E Albagha

Journal: Dis Model Mech

PubMed ID: 35229101

Doi: 10.1242/dmm.049318

Products & Services: Plasmid DNA Preparation

Recombinant human N-acetylneuraminate lyase as a tool to study clinically relevant mutant variants

Authors: Cheng Cheng, Zi-Xuan Hu, Meng He, Li Liu, Josef Voglmeir

Journal: Carbohydr Res

PubMed ID: 35487178

Doi: 10.1016/j.carres.2022.108561

Products & Services: Mammalian Expression

CLEVER assay: A visual and rapid RNA extraction-free detection of SARS-CoV-2 based on CRISPR-Cas integrated RT-LAMP technology

Authors: Akansha Bhatt, Zeeshan Fatima, Munindra Ruwali, Chitra Seetharam Misra, Shyam Sunder Rangu, Devashish Rath, Ashok Rattan, Saif Hameed

Journal: J Appl Microbiol

PubMed ID: 35396760

Doi: 10.1111/jam.15571

Products & Services: Plasmid DNA Preparation

Insect Cells for High-Yield Production of SARS-CoV-2 Spike Protein: Building a Virosome-Based COVID-19 Vaccine Candidate

Authors: Bárbara Fernandes, Rute Castro, Farien Bhoelan, Denzel Bemelman, Ricardo A Gomes, Júlia Costa, Patrícia Gomes-Alves, Toon Stegmann, Mario Amacker, Paula M Alves, Sylvain Fleury, António Roldão

Journal: Pharmaceutics

PubMed ID: 35456687

Doi: 10.3390/pharmaceutics14040854

Products & Services: Plasmid DNA Preparation

G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2

Authors: Wei Xu, Frank Bearoff, Sandhya Kortagere

Journal: Pharmacol Res

PubMed ID: 35429668

Doi: 10.1016/j.phrs.2022.106223

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models

Authors: Anurupa A Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim

Journal: Int J Mol Sci

PubMed ID: 35457082

Doi: 10.3390/ijms23084262

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Single-Molecule Catecholamine Enantiomers Using a Programmable Nanopore

Authors: Wendong Jia, Chengzhen Hu, Yuqin Wang, Yao Liu, Liying Wang, Shanyu Zhang, Qiang Zhu, Yuming Gu, Panke Zhang, Jing Ma, Hong-Yuan Chen, Shuo Huang

Journal: ACS Nano

PubMed ID: 35394745

Doi: 10.1021/acsnano.2c01017

Products & Services: Gene Synthesis

A Nanopore Based Molnupiravir Sensor

Authors: Wendong Jia , Chengzhen Hu , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: ACS Sens

PubMed ID: 35427117

Doi: 10.1021/acssensors.2c00447

Products & Services: Plasmid DNA Preparation

USP14-regulated allostery of the human proteasome by time-resolved cryo-EM

Authors: Shuwen Zhang , Shitao Zou , Deyao Yin , Lihong Zhao , Daniel Finley , Zhaolong Wu , Youdong Mao

Journal: Nature

PubMed ID: 35477760

Doi: 10.1038/s41586-022-04671-8

Products & Services: Gene Synthesis

Mechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning

Authors: Michael R Schamber , Reza Vafabakhsh

Journal: Nat Commun

PubMed ID: 35459864

Doi: 10.1038/s41467-022-29897-y

Products & Services: ORF cDNA Clones/MolecularCloud

Coenzyme B 12 -dependent and independent photoregulation of carotenogenesis across Myxococcales

Authors: Ricardo Pérez-Castaño , Eva Bastida-Martínez , Jesús Fernández-Zapata , María Del Carmen Polanco , María Luisa Galbis-Martínez , Antonio A Iniesta , Marta Fontes , S Padmanabhan , Montserrat Elías-Arnanz

Journal: Environ Microbiol

PubMed ID: 35005822

Doi: 10.1111/1462-2920.15895

Products & Services: Gene Synthesis

The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor

Authors: Francisco J Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E Shepard, Santiago Rodríguez de Córdoba, M Cristina Vega

Journal: Nat Commun

PubMed ID: 35413960

Doi: 10.1038/s41467-022-29580-2

Products & Services: Plasmid DNA Preparation

First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine

Authors: Luis Martínez, Iker Malaina, David Salcines-Cuevas, Héctor Terán-Navarro, Andrea Zeoli, Santos Alonso, Ildefonso M De la Fuente, Elena Gonzalez-Lopez, J Gonzalo Ocejo-Vinyals, Mónica Gozalo-Margüello, Jorge Calvo-Montes, Carmen Alvarez-Dominguez

Journal: Sci Rep

PubMed ID: 35440789

Doi: 10.1038/s41598-022-09615-w

Enhanced lipogenesis through Pparγ helps cavefish adapt to food scarcity

Authors: Shaolei Xiong, Wei Wang, Alexander Kenzior, Luke Olsen, Jaya Krishnan, Jenna Persons, Kyle Medley, Robert Peuß, Yongfu Wang, Shiyuan Chen, Ning Zhang, Nancy Thomas, John M Miles, Alejandro Sánchez Alvarado, Nicolas Rohner

Journal: Curr Biol

PubMed ID: 35390280

Doi: 10.1016/j.cub.2022.03.038

Products & Services: GenParts™ DNA Fragments

Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota

Authors: Matthew P Ostrowski, Sabina Leanti La Rosa, Benoit J Kunath, Andrew Robertson, Gabriel Pereira, Live H Hagen, Neha J Varghese, Ling Qiu, Tianming Yao, Gabrielle Flint, James Li, Sean P McDonald, Duna Buttner, Nicholas A Pudlo, Matthew K Schnizlein, Vincent B Young, Harry Brumer, Thomas M Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley A Eloe-Fadrosh, Ashootosh Tripathi, Phillip B Pope, Eric C Martens

Journal: Nat Microbiol

PubMed ID: 35365790

Doi: 10.1038/s41564-022-01093-0

Products & Services: GenParts™ DNA Fragments

Efficacy of convalescent plasma therapy in the patient with COVID-19: a randomised control trial (COPLA-II trial)

Authors: Meenu Bajpai, Ashish Maheshwari, Vikas Dogra, Suresh Kumar, Ekta Gupta, Pratibha Kale, Vandana Saluja, Sherin S Thomas, Nirupama Trehanpati, Chhagan Bihari, Reshu Agarwal, Praveen Bharti, Prabha Shankar, Javid Hussain, Karan Chhabra, Amita Gupta, Ashad Narayanan, Sarika Agarwal, Shruti Jain, Ankit Bhardwaj, Guresh Kumar, Birendra Kumar Yadav, Shiv Kumar Sarin

Journal: BMJ Open

PubMed ID: 35387813

Doi: 10.1136/bmjopen-2021-055189

Products & Services: Recombinant Proteins

Bioactive Hydrolysates from : Optimal Process and Bioactive Properties

Authors: Sara A Cunha, Ezequiel R Coscueta, Paulo Nova, Joana Laranjeira Silva, Maria Manuela Pintado

Journal: Molecules

PubMed ID: 35458702

Doi: 10.3390/molecules27082505

Products & Services: Catalog Peptides

Blocking TGF- Expression Attenuates Tumor Growth in Lung Cancers, Potentially Mediated by Skewing Development of Neutrophils

Authors: Yifei Fang, Xiyao Li, Yuxuan Jiang, Zhihan Ge

Journal: J Oncol

PubMed ID: 35498537

Doi: 10.1155/2022/3447185

Products & Services: Synthetic sgRNA and crRNA Service

Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

Authors: Jessica Hong, Hyung Joon Kwon, Raul Cachau, Catherine Z Chen, Kevin John Butay, Zhijian Duan, Dan Li, Hua Ren, Tianyuzhou Liang, Jianghai Zhu, Venkata P Dandey, Negin P Martin, Dominic Esposito, Uriel Ortega-Rodriguez, Miao Xu, Mario J Borgnia, Hang Xie, Mitchell Ho

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35476528

Doi: 10.1073/pnas.2201433119

Products & Services: Catalog Peptides

Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions

Authors: Yubai Zhou, Sandip Mukherjee, Daowei Huang, Molee Chakraborty, Chunfang Gu, Guangning Zong, Michael A Stashko, Kenneth H Pearce, Stephen B Shears, Anutosh Chakraborty, Huanchen Wang, Xiaodong Wang

Journal: J Med Chem

PubMed ID: 35467861

Doi: 10.1021/acs.jmedchem.2c00220

Products & Services: Mammalian Expression

Gene Expression in a Humanized 21-Hydroxylase Mouse Model Does Not Affect Adrenocortical Morphology and Function

Authors: Tina Schubert, Nicole Reisch, Ronald Naumann, Ilka Reichardt, Dana Landgraf, Friederike Quitter, Shamini Ramkumar Thirumalasetty, Anne-Kristin Heninger, Mihail Sarov, Mirko Peitzsch, Angela Huebner, Katrin Koehler

Journal: J Endocr Soc

PubMed ID: 35592511

Doi: 10.1210/jendso/bvac062

Products & Services: Plasmid DNA Preparation

Ferritin Light Chain: A Candidate Autoantigen in Immuno-Related Pancytopenia

Authors: Yang Zhang, Shanfeng Hao, Na Xiao, Yu Zhang, Huaquan Wang, Lijuan Li, Rong Fu, Zonghong Shao

Journal: Front Immunol

PubMed ID: 35572557

Doi: 10.3389/fimmu.2022.851096

Products & Services: Catalog Peptides

TXNDC9 knockdown inhibits lung adenocarcinoma progression by targeting YWHAG

Authors: Jing Wang, Xiaotao Pan, Jie Li, Jin Zhao

Journal: Mol Med Rep

PubMed ID: 35485284

Doi: 10.3892/mmr.2022.12719

Products & Services: Custom DNA/RNA Oligos

Efficient multinucleotide deletions using deaminase-Cas9 fusions in human cells

Authors: Siyu Chen, Zhiquan Liu, Hao Yu, Liangxue Lai, Zhanjun Li

Journal: J Genet Genomics

PubMed ID: 35421582

Doi: 10.1016/j.jgg.2022.03.007

Products & Services: Mutagenesis Services

Molecular spikes: a gold standard for single-cell RNA counting

Authors: Christoph Ziegenhain, Gert-Jan Hendriks, Michael Hagemann-Jensen, Rickard Sandberg

Journal: Nat Methods

PubMed ID: 35468967

Doi: 10.1038/s41592-022-01446-x

Products & Services: Gene Synthesis

NADH oxidase of Mycoplasma hyopneumoniae functions as a potential mediator of virulence

Authors: Fei Hao, Xing Xie, Zhixin Feng, Rong Chen, Yanna Wei, Jin Liu, Qiyan Xiong, Guoqing Shao, Johnson Lin

Journal: BMC Vet Res

PubMed ID: 35366872

Doi: 10.1186/s12917-022-03230-7

Products & Services: Bacterial Expression

Transcriptome analysis reveals the regulatory mechanism by which suppresses adventitious shoot formation in apple

Authors: Jiangping Mao, Doudou Ma, Chundong Niu, Xiaolong Ma, Ke Li, Muhammad Mobeen Tahir, Shiyue Chen, Xiuxiu Liu, Dong Zhang

Journal: Hortic Res

PubMed ID: 35669707

Doi: 10.1093/hr/uhac080

Products & Services: Polyclonal Antibody Services

Histone acetyltransferase GCN5-mediated lysine acetylation modulates salt stress aadaption of Trichoderma

Authors: Zhe Li, Hao Zhang, Chunjing Cai, Zhong Lin, Zhen Zhen, Jie Chu, Kai Guo

Journal: Appl Microbiol Biotechnol

PubMed ID: 35376971

Doi: 10.1007/s00253-022-11897-z

Products & Services: Polyclonal Antibody Services

Glycoside hydrolase from the GH76 family indicates that marine Salegentibacter sp Hel_I_6 consumes alpha-mannan from fungi

Authors: Vipul Solanki, Karen Krüger, Conor J Crawford, Alonso Pardo-Vargas, José Danglad-Flores, Kim Le Mai Hoang, Leeann Klassen, D Wade Abbott, Peter H Seeberger, Rudolf I Amann, Hanno Teeling, Jan-Hendrik Hehemann

Journal: ISME J

PubMed ID: 35414716

Doi: 10.1038/s41396-022-01223-w

Products & Services: Plasmid DNA Preparation

Deletion and tandem duplications of biosynthetic genes drive the diversity of triterpenoids in Aralia elata

Authors: Yu Wang, He Zhang, Hyok Chol Ri, Zeyu An, Xin Wang, Jia-Nan Zhou, Dongran Zheng, Hao Wu, Pengchao Wang, Jianfei Yang, Ding-Kun Liu, Diyang Zhang, Wen-Chieh Tsai, Zheyong Xue, Zhichao Xu, Peng Zhang, Zhong-Jian Liu, Hailong Shen, Yuhua Li

Journal: Nat Commun

PubMed ID: 35468919

Doi: 10.1038/s41467-022-29908-y

Products & Services: Custom Vector Construction

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

Authors: Nicholas K Hurlburt, Leah J Homad, Irika Sinha, Madeleine F Jennewein, Anna J MacCamy, Yu-Hsin Wan, Jim Boonyaratanakornkit, Anton M Sholukh, Abigail M Jackson, Panpan Zhou, Dennis R Burton, Raiees Andrabi, Gabriel Ozorowski, Andrew B Ward, Leonidas Stamatatos, Marie Pancera, Andrew T McGuire

Journal: Commun Biol

PubMed ID: 35411021

Doi: 10.1038/s42003-022-03262-7

Products & Services: Recombinant Proteins

Dynamic of anti-spike receptor binding domain (RBD) levels and short-term adverse events following a heterologous booster dose of BNT162b2 after two doses of CoronaVac in Thai health care workers

Authors: Amonrphat Kitro, Wachiranun Sirikul, Weeraya Thongkum, Suthinee Soponpong, Umpa Yasamut, Wuttipat Kiratipaisarl, Apiradee Kosai, Watchara Kasinrerk, Chatchai Tayapiwatana, Kriengkrai Srithanaviboonchai

Journal: Vaccine

PubMed ID: 35430106

Doi: 10.1016/j.vaccine.2022.04.020

Correction to "Febuxostat Prevents the Cytotoxicity of Propofol in Brain Endothelial Cells"

Authors: Jianli Hao, Weiqing Zhang, Rui Tong, Zeqing Huang

Journal: ACS Omega

PubMed ID: 35465124

Doi: 10.1021/acsomega.2c01716

Products & Services: Custom DNA/RNA Oligos

Topology of the Enterobacterial Common Antigen polymerase WzyE

Authors: Nicholas T Maczuga, Elizabeth N H Tran, Renato Morona

Journal: Microbiology (Reading)

PubMed ID: 35470793

Doi: 10.1099/mic.0.001183

Products & Services: Polyclonal Antibody Services

Recombinant Limosilactobacillus (Lactobacillus) delivering nanobodies against Clostridium perfringens NetB and alpha toxin confers potential protection from necrotic enteritis

Authors: Dharanesh Gangaiah, Valerie Ryan, Daphne Van Hoesel, Shrinivasrao P Mane, Enid T Mckinley, Nallakannu Lakshmanan, Nandakumar D Reddy, Edward Dolk, Arvind Kumar

Journal: Microbiologyopen

PubMed ID: 35478283

Doi: 10.1002/mbo3.1270

Products & Services: Proteins, Expression, Isolation and Analysis

NEAT1: Culprit lncRNA linking PIG-C, MSLN, and CD80 in triple-negative breast cancer

Authors: Nada H Hussein, Reda A Eissa, M de Bruyn, Hend M El Tayebi

Journal: Life Sci

PubMed ID: 35378140

Doi: 10.1016/j.lfs.2022.120523

Products & Services: Proteins, Expression, Isolation and Analysis

Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation

Authors: Fardokht Abulwerdi, Farzad Fatehi, Iain W Manfield, Stuart F J Le Grice, John S Schneekloth, Reidun Twarock, Peter G Stockley, Nikesh Patel

Journal: Data Brief

PubMed ID: 35516001

Doi: 10.1016/j.dib.2022.108206

Products & Services: Proteins, Expression, Isolation and Analysis

CCPG1 involved in corneal infection

Authors: Li-Mei Wang, Xiao-Meng Chen, Hai-Jing Yan, Shu Yan, Xiao-Yan Sun, Da-Wei Zhang, Hua Yang, Dan-Li Lu, Cheng-Ye Che

Journal: Int J Ophthalmol

PubMed ID: 35450172

Doi: 10.18240/ijo.2022.04.03

Products & Services: Proteins, Expression, Isolation and Analysis

Cloning and Organelle Expression of Bamboo Mitochondrial Complex I Subunits Nad1, Nad2, Nad4, and Nad5 in the Yeast

Authors: Hsieh-Chin Tsai, Cheng-Hung Hsieh, Ching-Wen Hsu, Yau-Heiu Hsu, Lee-Feng Chien

Journal: Int J Mol Sci

PubMed ID: 35409414

Doi: 10.3390/ijms23074054

Products & Services: Catalog Antibody

Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects

Authors: Dohee Ahn, Jinsoo Kim, Gibeom Nam, Xiaodi Zhao, Jihee Kwon, Ji Young Hwang, Jae Kwan Kim, Sun-Young Yoon, Sang J Chung

Journal: Int J Mol Sci

PubMed ID: 35563411

Doi: 10.3390/ijms23095020

Products & Services: Gene Synthesis

LPS Response Is Impaired by Urban Fine Particulate Matter

Authors: Natália de Souza Xavier Costa, Gabriel Ribeiro Júnior, Adair Aparecida Dos Santos Alemany, Luciano Belotti, Marcela Frota Cavalcante, Susan Ribeiro, Mariana Matera Veras, Esper Georges Kallás, Paulo Hilário Nascimento Saldiva, Marisa Dolhnikoff, Luiz Fernando Ferraz da Silva

Journal: Int J Mol Sci

PubMed ID: 35409273

Doi: 10.3390/ijms23073913

Products & Services: Endotoxin Detection & Removal System

Identification and characterization of novel endolysins targeting Gardnerella vaginalis biofilms to treat bacterial vaginosis

Authors: Sara Arroyo-Moreno, Matthew Cummings, David B Corcoran, Aidan Coffey, Ronan R McCarthy

Journal: NPJ Biofilms Microbiomes

PubMed ID: 35440653

Doi: 10.1038/s41522-022-00285-0

Products & Services: Proteins, Expression, Isolation and Analysis

MicroRNA-217 modulates pancreatic cancer progression via targeting ATAD2

Authors: Madhuri Dutta, Biswajit Das, Debasish Mohapatra, Padmanava Behera, Shantibhusan Senapati, Anasuya Roychowdhury

Journal: Life Sci

PubMed ID: 35504332

Doi: 10.1016/j.lfs.2022.120592

Products & Services: Recombinant Proteins

Peptide Permeation across a Phosphocholine Membrane: An Atomically Detailed Mechanism Determined through Simulations and Supported by Experimentation

Authors: Alfredo E Cardenas, Chad I Drexler, Rachel Nechushtai, Ron Mittler, Assaf Friedler, Lauren J Webb, Ron Elber

Journal: J Phys Chem B

PubMed ID: 35388695

Doi: 10.1021/acs.jpcb.1c10966

Products & Services: Peptide Synthesis

« 上一页
112
113
114
115
116
117
118
119
120
下一页 »

客户发表文献

资源中心

技术支持

关于我们