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Exploring the substrate spectrum of phylogenetically distinct bacterial polyesterases

Authors: Konstantinos Makryniotis, Efstratios Nikolaivits, George Taxeidis, Jasmina Nikodinovic-Runic, Evangelos Topakas

Journal: Biotechnol J

PubMed ID: 38593303

Doi: 10.1002/biot.202400053

Products & Services: Molecular Biology Reagents

Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR

Authors: Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker

Journal: SCIENCE ADVANCES

PubMed ID: 37986777

Doi: 10.1101/2023.10.05.561100

Products & Services: Proteins, Expression, Isolation and Analysis

CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing

Authors: Eleonora Pedrazzoli, Michele Demozzi, Elisabetta Visentin, Matteo Ciciani, Ilaria Bonuzzi, Laura Pezzè, Lorenzo Lucchetta, Giulia Maule, Simone Amistadi, Federica Esposito, Mariangela Lupo, Annarita Miccio, Alberto Auricchio, Antonio Casini, Nicola Segata, Anna Cereseto

Journal: Nat Commun

PubMed ID: 38658578

Doi: 10.1038/s41467-024-47800-9

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Delivering large genes using adeno-associated virus and the CRE-lox DNA recombination system

Authors: Poppy Datta, Kun Do Rhee, Rylee J Staudt, Jacob M Thompson, Ying Hsu, Salma Hassan, Arlene V Drack, Seongjin Seo

Journal: Human Molecular Genetics

PubMed ID: 38645107

Doi: 10.1101/2024.04.10.588864

Products & Services: PCR and Cloning ORF cDNA Clones/MolecularCloud

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Authors: Madison A Ward, Janakiram R Vangala, Hatem Elif Kamber Kaya, Holly A Byers, Nayyerehalsadat Hosseini, Antonio Diaz, Ana Maria Cuervo, Susmita Kaushik, Senthil K Radhakrishnan

Journal: J Cell Biol

PubMed ID: 38656405

Doi: 10.1083/jcb.202306150

Products & Services: Molecular Biology Reagents

Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis

Authors: Xinran Wang, Ningxin Chen, Pablo Cruz-Morales, Biming Zhong, Yangming Zhang, Jian Wang, Yifan Xiao, Xinnan Fu, Yang Lin, Suneil Acharya, Zhibo Li, Huaxiang Deng, Yuhui Sun, Linquan Bai, Xiaoyu Tang, Jay D Keasling, Xiaozhou Luo

Journal: Nat Metab

PubMed ID: 38609677

Doi: 10.1038/s42255-024-01024-9

Products & Services: Gene Synthesis

Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC receptor

Authors: Zoe Tasma, Tayla A Rees, Song Guo, Sheryl Tan, Simon J O'Carroll, Richard L M Faull, Maurice A Curtis, Sarah L Christensen, Debbie L Hay, Christopher S Walker

Journal: Br J Pharmacol

PubMed ID: 38616050

Doi: 10.1111/bph.16376

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibition of USP7 enhances CD8 T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation

Authors: Lin-Lin Sun, Li-Na Zhao, Jiao Sun, Hong-Feng Yuan, Yu-Fei Wang, Chun-Yu Hou, Pan Lv, Hui-Hui Zhang, Guang Yang, Ning-Ning Zhang, Xiao-Dong Zhang, Wei Lu

Journal: Acta Pharmacol Sin

PubMed ID: 38589688

Doi: 10.1038/s41401-024-01263-2

Products & Services: Custom Vector Construction

Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling

Authors: Luca Unione, Augustinus N A Ammerlaan, Gerlof P Bosman, Elif Uslu, Ruonan Liang, Frederik Broszeit, Roosmarijn van der Woude, Yanyan Liu, Shengzhou Ma, Lin Liu, Marcos Gómez-Redondo, Iris A Bermejo, Pablo Valverde, Tammo Diercks, Ana Ardá, Robert P de Vries, Geert-Jan Boons

Journal: Nat Commun

PubMed ID: 38582892

Doi: 10.1038/s41467-024-47344-y

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis

Authors: Yu Jeong Choi, Yoonjung Kim, Hye Jung Park, Dokyun Kim, Hyukmin Lee, Young Ah Kim, Kyung-A Lee

Journal: Ann Clin Microbiol Antimicrob

PubMed ID: 38581051

Doi: 10.1186/s12941-024-00687-2

Products & Services: Molecular Biology Reagents

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