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Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
Authors: Rosa Antón, Miguel Á Treviño, David Pantoja-Uceda, Sara Félix, María Babu, Eurico J Cabrita, Markus Zweckstetter, Philip Tinnefeld, Andrés M Vera, Javier Oroz
Journal: Nature
PubMed ID: 38431667
Doi: 10.1038/s41467-024-46236-5
Products & Services: Gene Synthesis   
An alphacoronavirus polymerase structure reveals conserved replication factor functions
Authors: Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer
Journal: Nucleic Acids Research
PubMed ID: 38442273
Doi: 10.1093/nar/gkae153
Products & Services: Codon Optimization   
Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets 
Authors: Eric A Nalefski, Remy M Kooistra, Ishira Parikh, Samantha Hedley, Karunya Rajaraman, Damian Madan
Journal: Nucleic Acids Research
PubMed ID: 38477377
Doi: 10.1093/nar/gkae152
Products & Services: Gene Synthesis   
A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer
Authors: Pei-Zhen Han, Wei-Dong Ye, Peng-Cheng Yu, Li-Cheng Tan, Xiao Shi, Xu-Feng Chen, Cong He, Jia-Qian Hu, Wen-Jun Wei, Zhong-Wu Lu, Ning Qu, Yu Wang, Qing-Hai Ji, Dong-Mei Ji, Yu-Long Wang
Journal: JCI Insight
PubMed ID: 38478516
Doi: 10.1172/jci.insight.173712
Products & Services: Molecular Biology Reagents   
Structurally Diverse Bisbenzylisoquinoline Alkaloids with Antiadipogenic Activity through Downregulation from the Embryo of Seeds
Authors: Peiliang Zhang, Jiadong Li, Jiyao Shi, Zhihong Cheng, Tao Wu
Journal: J Nat Prod
PubMed ID: 38483204
Doi: 10.1021/acs.jnatprod.3c01290
Products & Services: Proteins, Expression, Isolation and Analysis   
Immunoprotective effect and mechanism of rEgP29 against CD4 T cell-deficient mice with infection
Authors: Ming Li, Yazhou Zhu, Zihua Li, Jiahui Song, Wei Zhao
Journal: Acta Biochim Biophys Sin (Shanghai)
PubMed ID: 38151996
Doi: 10.3724/abbs.2023282
Products & Services: Molecular Biology Reagents   
Separation and purification of short-, medium-, and long-stranded RNAs by RP-HPLC using different mobile phases and C columns with various pore sizes
Authors: Makoto Ozaki, Tomomi Kuwayama, Motoshi Shimotsuma, Tsunehisa Hirose
Journal: Anal Methods
PubMed ID: 38445900
Doi: 10.1039/d4ay00114a
Products & Services: Gene Synthesis   
Exploring the enigmatic association between PNLIP variants and risk of chronic pancreatitis in a large Chinese cohort
Authors: Brett M Cassidy, Fei Jiang, Jianguo Lin, Jian-Min Chen, Grace E Curry, Guo-Xiu Ma, Steven J Wilhelm, Shun-Jiang Deng, Guoying Zhu, Zhuan Liao, Mark E Lowe, Xunjun K Xiao, Wen-Bin Zou
Journal: Pancreatology
PubMed ID: 38485544
Doi: 10.1016/j.pan.2024.03.002
Products & Services: Mutagenesis Services   
WDR4 promotes HCC pathogenesis through N-methylguanosine by regulating and interacting with METTL1
Authors: Rui Dong, Chuanxu Wang, Bo Tang, Yayu Cheng, Xuehui Peng, Xiaomin Yang, Bing Ni, Jing Li
Journal: Cell Signal
PubMed ID: 38493882
Doi: 10.1016/j.cellsig.2024.111145
Products & Services: Proteins, Expression, Isolation and Analysis   
Inhibitory effects of senkyuchachosan on SARS-CoV-2 papain-like protease activity in vitro
Authors: Yuka Kiba, Takashi Tanikawa, Tsuyoshi Hayashi, Takami Yokogawa, Aiko Sano, Ryuichiro Suzuki, Masashi Kitamura
Journal: J Nat Med
PubMed ID: 38512650
Doi: 10.1007/s11418-024-01788-0
Products & Services: Molecular Biology Reagents   

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